PE/Fire™ 700 anti-mouse CD278 (ICOS) Antibod
- 产品名称：
- PE/Fire™ 700 anti-mouse CD278 (ICOS) Antibod
- 产品类别：
- 抗体
- 产品编号：
- 107715
- 产品应用：
- 107715
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Syrian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE/Fire? 700 under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
* PE/Fire? 700 has a maximum excitation of 565 nm and a maximum emission of 695 nm.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining2 of acetone-fixed frozen sections.
- Application References
(PubMed link indicates BioLegend citation) -
- Dong C, et al. 2001. Nature 409(6816):97.
- Walker LSK, et al. 2003. J. Immunol. 170:91.
- RRID
- AB_2924446 (BioLegend Cat. No. 107715) AB_2924446 (BioLegend Cat. No. 107716)
- Structure
- CD28/CTLA-4, 47-57kD
- Distribution
-
Activated T cells, subset of thymocytes
- Function
- Costimulates T cell activation, proliferation, humoral immune response
- Ligand/Receptor
- B7h/B7RP-1/GL-50
- Cell Type
- T cells, Thymocytes, Tregs
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Rudd CE, et al. 2003. Nat. Rev. Immunol. 3:544.
- McAdam AJ, et al. 2000. J. Immunol. 165:5035.
- Mak TW, et al. 2003. Nat. Immunol. 4:765
- Gene ID
- 54167 View all products for this Gene ID
- UniProt
- View information about CD278 on UniProt.org
