APC anti-mouse CD278 (ICOS) Antibody
- 产品名称:
- APC anti-mouse CD278 (ICOS) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 107711
- 产品应用:
- 107711
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Syrian Hamster
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemical staining2 of acetone-fixed frozen sections.
- Application References
(PubMed link indicates BioLegend citation) -
- Dong C, et al. 2001. Nature 409(6816):97.
- Walker LSK, et al. 2003. J. Immunol. 170:91.
- Product Citations
-
- Ogbechi J, et al. 2022. Front Immunol. 13:1001956. PubMed
- Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
- RRID
- AB_2728128 (BioLegend Cat. No. 107711) AB_2728129 (BioLegend Cat. No. 107712)
- Disclaimer
This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated then a license must be requested from the University of California. The availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.
- Structure
- CD28/CTLA-4, 47-57kD
- Distribution
-
Activated T cells, subset of thymocytes
- Function
- Costimulates T cell activation, proliferation, humoral immune response
- Ligand/Receptor
- B7h/B7RP-1/GL-50
- Cell Type
- T cells, Thymocytes, Tregs
- Biology Area
- Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Rudd CE, et al. 2003. Nat. Rev. Immunol. 3:544.
- McAdam AJ, et al. 2000. J. Immunol. 165:5035.
- Mak TW, et al. 2003. Nat. Immunol. 4:765
- Gene ID
- 54167 View all products for this Gene ID
- UniProt
- View information about CD278 on UniProt.org