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APC anti-mouse CD278 (ICOS) Antibody
产品名称:
APC anti-mouse CD278 (ICOS) Antibody
产品类别:
抗体
产品编号:
107711
产品应用:
107711
[价格]
规格 价格 库存
25µg ¥ 1428 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Syrian Hamster
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining2 of acetone-fixed frozen sections.

Application References

(PubMed link indicates BioLegend citation)
  1. Dong C, et al. 2001. Nature 409(6816):97.
  2. Walker LSK, et al. 2003. J. Immunol. 170:91.
Product Citations
  1. Ogbechi J, et al. 2022. Front Immunol. 13:1001956. PubMed
  2. Yang W, et al. 2020. Mucosal Immunol. 13:788. PubMed
RRID
AB_2728128 (BioLegend Cat. No. 107711) AB_2728129 (BioLegend Cat. No. 107712)
Disclaimer

This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated then a license must be requested from the University of California. The availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.

Antigen Details

Structure
CD28/CTLA-4, 47-57kD
Distribution

Activated T cells, subset of thymocytes

Function
Costimulates T cell activation, proliferation, humoral immune response
Ligand/Receptor
B7h/B7RP-1/GL-50
Cell Type
T cells, Thymocytes, Tregs
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References
  1. Rudd CE, et al. 2003. Nat. Rev. Immunol. 3:544.
  2. McAdam AJ, et al. 2000. J. Immunol. 165:5035.
  3. Mak TW, et al. 2003. Nat. Immunol. 4:765
Gene ID
54167 View all products for this Gene ID
UniProt
View information about CD278 on UniProt.org

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