APC anti-human CD369 (Dectin-1/CLEC7A) Antibody
- 产品名称：
- APC anti-human CD369 (Dectin-1/CLEC7A) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 355405
- 产品应用：
- 355405
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2254 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Ectodomain with C-term hFc fusion, RIBLS.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
The epitope of clone 15E2 is LWEDGSTFSSN. Clone 15E2 can recognize the epitope in the presence of Curdlan and Laminarin (CLEC7A ligands). Additional reported applications (for the relevant formats) include: immunohistochemical staining.1
- Application References
(PubMed link indicates BioLegend citation) -
- Ni L, et al. 2010. J. Immunol. 185:3504. (IHC)
- RRID
- AB_2800956 (BioLegend Cat. No. 355405) AB_2800957 (BioLegend Cat. No. 355406)
- Structure
- Type II transmemberane C-type lectin, one carbohydrate recognition domain, ITAM containing cytoplasmic tail
- Distribution
-
B cells, low level of some subsets of T cells, monocytes, dendritic cells, macrophages and endothelial cells
- Function
- Mediates innate immunity to fungal pathogens
- Interaction
- TLR2, CD37
- Ligand/Receptor
- Beta-glucan
- Cell Type
- B cells, Dendritic cells, Endothelial cells, Macrophages, Monocytes, T cells
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
-
1. Goodridge HS, et al. 2011. Nature 472:471.
2. Saijo S, et al. 2007. Nat. Immunol. 8:39.
3. Brown GD. 2006. Nat. Rev. Immunol. 6:33.
4. Willment JA, et al. 2001. J. Biol. Chem. 276:43818.
5. Yokota K, et al. 2001. Gene 272:51.
- Gene ID
- 64581 View all products for this Gene ID
- UniProt
- View information about CD369 on UniProt.org
