PE anti-human LOX-1 Antibody
- 产品名称：
- PE anti-human LOX-1 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 358603
- 产品应用：
- 358603
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2142 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- LOX-1 ectodomain: Fc fusion protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunofluorescent staining of acetone-fixed frozen human skin sections1.
- Application References
(PubMed link indicates BioLegend citation) -
- Li D, et al. 2012. J. Exp. Med. 209:109. (IHC)
- Product Citations
-
- Tu J, et al. 2022. Adv Sci (Weinh). 9:e2103631. PubMed
- Thompson EA, et al. 2021. Cell Rep. 108863:34. PubMed
- RRID
- AB_2562180 (BioLegend Cat. No. 358603) AB_2562181 (BioLegend Cat. No. 358604)
- Structure
- Single pass, type II, transmembrane protein, 31 kD, homodimer, member of the C-type lectin superfamily.
- Distribution
- Endothelial cells, smooth muscle, platelets, fibroblasts, macrophages; Upregulated by inflammatory and oxidative stimuli
- Function
- Scavenger receptor, involved in endocytosis, phagocytosis and cytokine production
- Ligand/Receptor
- Recognizes numerous ligands including lipoproteins, apoptotic cells, heat shock proteins, C-reactive protein, oxidized LDL
- Cell Type
- Endothelial cells, Platelets, Fibroblasts, Macrophages, Dendritic cells
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules
- Antigen References
-
1. Yin Y, et al. 2013. Eur. J. Cell Biol. 92:150.?
2. Khaidakov M. and Mehta JL. 2012. PLoS One. 7:e46973.?
3. Sawamura T, et al. 2012. Curr. Opin. Lipidol. 23:439.?
4. Lin FY, et al. 2011. J. Immunol. 186:4405.?
5. Parlato S, et al. 2010. Blood 115:1554.
- Gene ID
- 4973 View all products for this Gene ID
- UniProt
- View information about LOX-1 on UniProt.org
