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PE/Cyanine7 anti-β Catenin 1 Antibody
产品名称:
PE/Cyanine7 anti-β Catenin 1 Antibody
产品类别:
抗体
产品编号:
862605
产品应用:
862605
[价格]
规格 价格 库存
25tests ¥ 2884 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Guo J, et al. 2018. Cell Res. 28:1141 (IHC-P)
  2. Kisoh K, et al. 2017. Mol Neurobiol. 54:7917 (WB)
  3. Uribe RA, et al. 2015. J Cell Biol. 4:815 (IHC-F)
RRID
AB_2927830 (BioLegend Cat. No. 862605)

Antigen Details

Structure
β Catenin is a 781 amino acid protein with an apparent molecular mass of ~ 86 kD.
Distribution

Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Plasma membrane, cytoskeleton, nucleus, cytosol, and extracellular

Function
β Catenin is a dual functional protein involved in cell-cell adhesion and gene transcription.
Interaction
E-cadherin/CDH1, LEF1, TCF4, etc.
Antigen References
  1. Dias C, et al. 2014. Nature. 516(7529): 51
  2. Rosiles A, et al. 2016. CNS Neurol Disord Drug Targets. 15(1):3
  3. Na K, et al. 2017. Anticancer Res. 37(6):3249
  4. Zhu P, et al. 2018. Cancer Res Treat. 50(4):1452
Gene ID
1499 View all products for this Gene ID 12387 View all products for this Gene ID 84353 View all products for this Gene ID
UniProt
View information about beta Catenin 1 on UniProt.org

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