PE anti-mouse/rat/human FOXP3 Antibody
- 产品名称：
- PE anti-mouse/rat/human FOXP3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 320007
- 产品应用：
- 320007
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 2828 |
1 |
- Verified Reactivity
- Human, Mouse, Rat
- Reported Reactivity
- Cynomolgus, Rhesus, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full-length FOXP3 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The FOXP3 antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular flow cytometry using our True-Nuclear? Transcription Factor Staining Protocol. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
NOTE: For flow cytometric staining with this clone, True-Nuclear? Transcription Factor Buffer Set (Cat. No. 424401) offers improved staining and is highly recommended.
- Additional Product Notes
View more applications data for this product in our Scientific Poster Library.
- Application References
(PubMed link indicates BioLegend citation) -
- Roncador G, et al. 2005 Eur. J. Immunol. 35:1681.
- Mayack. S,et al. 2006. J. Immunol.176:2059. J. Immunol
- Yang ZZ, et al. 2006. Blood 107:3639.
- Gavin MA, et al. 2006. P. Natl. Acad. Sci. USA 103:6659.
- Groh V, et al. 2006. Nature Immunology 7:755.
- Lewkowicz P, et al. 2006 J. Immunol. 177:7155.
- Luke PPW, et al. 2006. Amer. J. Transplant. 6(9):2023.
- Bamias G, et al. 2007. J. Immunol. 178:1809.
- Valencia X, et al. 2007. J. Immunol. 178:2579.PubMed
- Davidson TS, et al. 2007. J. Immunol. 178:4022.
- MacDonald K PA, et al. 2007. Blood doi:10.1182/blood-2007-01-067249.
- Jaffar Z, et al. 2007. J. Immunol. 179:6193.
- Müller M, et al. 2007. J. Immunol. 179:2774.
- Jordan JM,et al. 2008.Infect Human. 76:3717. PubMed
- Golovina TN,et al. 2008. J. Immunol. 181:2855. PubMed
- Fallarino F, et al. 2009. J. Exp Med. 206:2511. PubMed
- Banham Alison, et al. 2009. Vet Immunol and Immunop 127.3-4:376-381
- Klunker S, et al. 2009. J. Exp Med. PubMed
- Haque A, et al. 2010. J. Immunol. 184:2583. PubMed
- Liu Y, et al. 2012. Food Chem Toxicol. 50:1920. PubMed
- Product Citations
-
- Tian J, et al. 2021. Autophagy. 17:2586. PubMed
- Mishra R, et al. 2022. J Transl Med. 20:323. PubMed
- Cheng L, et al. 2021. Cancer Immunol Immunother. Online ahead of print. PubMed
- Chen L, et al. 2022. Mol Ther Oncolytics. 24:522. PubMed
- Lin H, et al. 2020. Front Microbiol. 1.330555556. PubMed
- Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
- Lu Y, et al. 2020. Cell. 180(6):1081-1097. PubMed
- Gorczynski RM, et al. 2017. Immunology. 150:418. PubMed
- Zongyi Y, et al. 2017. PLoS One. 10.1371/journal.pone.0189617. PubMed
- Casadesús AV, et al. 2020. Oncoimmunology. 9:1770565. PubMed
- Wei JL, et al. 2021. J Immunother Cancer. 9: . PubMed
- Levi J, et al. 2020. J Nucl Med. . PubMed
- Deng Z, et al. 2020. World J Gastrointest Oncol. 1091:12. PubMed
- Kennedy EM, et al. 2022. Nat Commun. 13:5907. PubMed
- Momin N, et al. 2022. Nat Commun. 13:109. PubMed
- Zhu Y, et al. 2021. EMBO J. 40:e105320. PubMed
- Tian X, et al. 2022. J Cell Mol Med. 26:693. PubMed
- Su X, et al. 2022. J Transl Med. 20:378. PubMed
- Fang J, et al. 2014. J Neuroimmunol. 269:9. PubMed
- Sydney Lavoie et al. 2019. eLife. 8 pii: e39982. PubMed
- Wang R, et al. 2022. Front Immunol. 13:947756. PubMed
- Lü X, et al. 2021. Exp Ther Med. 22:1005. PubMed
- Yang Z, et al. 2021. Onco Targets Ther. 14:4239. PubMed
- Zeng Q, et al. 2022. iScience. 25:105151. PubMed
- Huang J, et al. 2014. J Immunol. 192:1972. PubMed
- Ouyang S, et al. 2019. J Immunol. 202:1441. PubMed
- He S, et al. 2021. Front Pharmacol. 12:743837. PubMed
- Wang S, et al. 2022. J Inflamm Res. 14:7107. PubMed
- Tanaka S, et al. 2016. Appl Envir Microbiol. 82: 2693 - 2699. PubMed
- Wang J, et al. 2019. Aging (Albany NY). 11:3463. PubMed
- Chen KH, et al. 2019. J Neuropathol Exp Neurol. 78:65. PubMed
- Jia Y, et al. 2022. J Transl Med. 20:281. PubMed
- Loo Yau H, et al. 2021. Molecular Cell. 81(7):1469-1483.e8. PubMed
- Lu Y, et al. 2018. Cancer Cell. 33:1048. PubMed
- Zhu P, et al. 2022. Cell Commun Signal. 20:121. PubMed
- Rana MN, et al. 2021. Front Pharmacol. 12:643215. PubMed
- RRID
- AB_492981 (BioLegend Cat. No. 320007) AB_492980 (BioLegend Cat. No. 320008)
- Structure
- Forkhead/winged-helix transcription factor family, approximately 50 kD, contains zinc finger and forkhead domains
- Distribution
-
Nuclear; expressed in T regulatory cells
- Function
- Transcription factor proposed to be a master regulatory gene in T regulatory cell development and a critical factor for immune homeostasis
- Interaction
- Interacts with DNA
- Cell Type
- Tregs
- Biology Area
- Cell Biology, Immunology, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Hori S, et al. 2003. Science 299:1057.
- Regulation
- FOXP3 is present at high levels in T regulatory cell can also be induced by T cell activation
- Gene ID
- 20371 View all products for this Gene ID 317382 View all products for this Gene ID 50943 View all products for this Gene ID
- UniProt
- View information about FOXP3 on UniProt.org
