Purified anti-Rad23B Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 147	1

规格

价格

库存

25µg

￥ 147

Product Details

Verified Reactivity: Mouse, Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Full length recombinant human Rad23B protein.
Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Preparation: Protein G affinity purified.
Concentration: 0.5 mg/ml
Storage & Handling: Upon receipt, store undiluted between 2°C and 8°C.
Application: WB - Quality tested
KO/KD-WB - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: Rad23B has two isoforms, and the predicted Mws are 43kD and 35kD respectively. For 43kD isoform, the observed Mw is 53kD.
RRID: AB_2561795 (BioLegend Cat. No. 654201)

Structure: 409 amino acids, predicted molecular weight of 43 kD
Distribution: Nucleus, cytoplasm (the intracellular distribution is cell cycle dependent)
Function: Modulation of proteasomal degradation; involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex
Interaction: Component of the XPC complex composed of XPC, RAD23B and CETN2; interacts with NGLY1, PSMC1, ATXN3, PSMD4, PSMC5, and AMFR
Cell Type: B cells
Biology Area: Cell Biology, Immunology, Ubiquitin/Protein Degradation
Antigen References: 1. Sugasawa K, et al. 1997. Mol. Cell Biol. 17:6924.
2. Thoma BS and Vasquez KM. 2003. Mol. Carcinog. 38:1.
3. Reina CP, et al. 2010. Hum. Mol. Genet. 19:235.
4. Farmer LM, et al. 2010. Plant Cell 22:124.
5. Khan O, et al. 2010. Proc. Natl. Acad. Sci. USA 107:6532.
6. Kamiya Y, et al. 2012. FEBS Lett. 586:1141.
Gene ID: 5887 View all products for this Gene ID
UniProt: View information about Rad23B on UniProt.org