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HRP anti-FUS Antibody
产品名称：
HRP anti-FUS Antibody
英文名称：
型号：
855003
产品库存：
1
产品价格：
电议

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Human TLS/FUS recombinant protein fused with GST tag.
Formulation
This antibody is provided in 50% glycerol in aqueous buffered solutions with preservatives.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.05 - 0.2 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2783440 (BioLegend Cat. No. 855003) AB_2783441 (BioLegend Cat. No. 855004)

Antigen Details

Structure
FUS is a 526 amino acid protein with an apparent molecular mass of ~ 53 kD.
Distribution

Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Nucleus and cytosol

Function
FUS/TLS binds to DNA and maintains genomic integrity.
Interaction
Interacts with HDAC1, RNA Polymerase II, FUSIP1, ILF3, PRMT1, RELA, SPI1, and TNPO1.
Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Synaptic Biology
Molecular Family
Postsynaptic proteins, Presynaptic proteins
Antigen References
  1. Efimova AD, et al. 2017. Mol Biol (Mosk) 51:387.
  2. Ederle H, Dormann D. 2017. FEBS Lett. 591:1489.
  3. Guerrero EN, et al. 2016. Prog. Neurobiol. 145-146:78.
Gene ID
2521 View all products for this Gene ID 233908 View all products for this Gene ID 217385 View all products for this Gene ID
UniProt
View information about FUS on UniProt.org

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