APC anti-mouse CD226 (DNAM-1) Antibody
- 产品名称：
- APC anti-mouse CD226 (DNAM-1) Antibody
- 英文名称：
- 型号：
- 128809
- 产品库存：
- 1
- 产品价格：
- 电议
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Th1 polarized T cell clones
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Dardalhon V, et al. 2005. J. Immunol. 175:1558
- Huang Z, et al. 2011. J Immunol. 186:3421. PubMed
- Product Citations
-
- Chan S, et al. 2022. Nat Cancer. . PubMed
- Afolabi LO, et al. 2021. Front Immunol. 12:701671. PubMed
- Anderson DA, et al. 2022. J Exp Med. 219:. PubMed
- RRID
- AB_2566626 (BioLegend Cat. No. 128809) AB_2566627 (BioLegend Cat. No. 128810)
- Structure
- 65 kd glycoprotein of a member of Ig-superfamily containing 2 immunologlobulin-like domains.
- Distribution
-
Expressed on majority of CD4+ and CD8+ T cells, NK cells, monocytes/macrophages and a subset of B cells and thymocytes. Reported to be specifically expressed on the surface of Th1 cells, but downregulated in Th2 cells.
- Function
- Mediates cellular adhesion, involved in LFA-1 costimulatory signal for T cell differentiation and proliferation
- Ligand/Receptor
- CD112 and CD155
- Cell Type
- B cells, Macrophages, Monocytes, NK cells, T cells, Th1
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1.Tahara Hanaoka S, et al. 2006. Blood 107:1491
2. Shibuya K, et al. 2003. J. Exp. Med. 198:1829
- Gene ID
- 225825 View all products for this Gene ID
- UniProt
- View information about CD226 on UniProt.org
