Alexa Fluor® 488 anti-Tubulin-α Antibody
- 产品名称：
- Alexa Fluor® 488 anti-Tubulin-α Antibody
- 英文名称：
- 型号：
- 627905
- 产品库存：
- 1
- 产品价格：
- 电议
- Verified Reactivity
- Human, Mouse, Rat, All Species
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant full length human α-tubulin
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide at 0.5 mg/ml.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICC?- Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistrys, a concentration range of 1.0 - 4.0 ?g/mL?is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses - Excitation Laser
- Blue Laser (488 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Chou HYE, et al. 2006. J. Biol. Chem. 281:15201.
- Product Citations
-
- Ziegler CGK, et al. 2021. Cell. 184(18):4713-4733.e22. PubMed
- Khalin I, et al. 2020. ACS Nano. 14:9755. PubMed
- RRID
- AB_893643 (BioLegend Cat. No. 627905) AB_893642 (BioLegend Cat. No. 627906)
- Structure
- Tubulin family, tubulin is a dimeric protein consisting of an alpha and beta chain. Alpha tubulin has an approximate molecular weight of 50-55 kD.
- Distribution
-
Ubiquitous
- Function
- Tubulin is one of the major constituents of microtubules. Binds GTP, alpha chain contains a non-exchangeable GTP binding site
- Interaction
- RAC GTPase activating protein 1, ZAP70, Polo-like kinase, c-Myc, Fyn, Microtubule associated protein 1A
- Modification
- Phosphorylation, acetylation
- Biology Area
- Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Microtubules
- Antigen References
-
1. Cowan NJ, et al. 1983. Mol. Cell. Biol. 3:1738.
2. Miller FD, et al. 1987. J. Cell Biol. 105:3065.
3. Wilde CD, et al. 1982. Proc. Natl. Acad. Sci. USA 79:96.
- Gene ID
- 84790 View all products for this Gene ID
- UniProt
- View information about Tubulin-alpha on UniProt.org
