Purified anti-human/rat CD51 (Integrin αv&be-上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 1344	1

Product Details

Verified Reactivity: Human, Rat
Reported Reactivity: Hamster
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: The P1F6 monoclonal antibody was generated against human small cell lung carcinoma cells (UCLA P3).
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.50 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application Notes: P1F6, reacts with the av?5 integrin complex. This antibody does not cross react with any other av containing integrin and completely inhibits av?5 dependent binding to vitronectin coated surfaces.
RRID: AB_2571949 (BioLegend Cat. No. 920004)

Structure: Two disulfide-linked subunits of 125 kD and 24 kD.
Distribution: Endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells.
Function: As an adhesion molecule, it plays important roles in leukocytes homing and rolling as well as mediates bone absorption and angiogenesis.
Interaction: Forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8.
Cell Type: Endothelial cells, Fibroblasts, Macrophages, Mesenchymal Stem Cells, Osteoclasts, Platelets
Biology Area: Cell Adhesion, Cell Biology, Costimulatory Molecules, Neuroscience, Stem Cells, Synaptic Biology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Burvenich I, et al. 2008. Mol. Cancer Ther. 7(12):3771.
2. Lee P, et al. 2014. J. Biol. Chem. 289(3):1467.
3. Su G, et al. 2007. Am. J. Respir. Cell Mol. Biol. 36(3):377.
4. Wayner EA, et al. 2007. Methods in Enzymology 426:117.
5. Weinacker A, et al. 1994. J. Biol. Chem. 269(9):6940.
Gene ID: 3685 View all products for this Gene ID
UniProt: View information about CD51 on UniProt.org