Purified anti-human CD49b Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 1212	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

HT1080 cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IP, ELISA - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats of this clone) include: in vitro blocking activity^1,2, immunoprecipitation³, and ELISA⁴.?

Application References (PubMed link indicates BioLegend citation)

Hirsch MS, et al. 1997. Dev. Dyn. 210:249. (Block)
Sawhney RS, et al. 2006. J. Biol. Chem. 281:8497. (Block)
Lee SA, et al. 2009. Carcinogensis. 30:1872. (IP)
Z?rate S, et al. 2004. J. Virol. 78:10839. (ELISA)

Product Citations

Watanabe K, et al. 2018. Am J Physiol Cell Physiol. 315:C398. PubMed

RRID

AB_2562681 (BioLegend Cat. No. 359301) AB_2562682 (BioLegend Cat. No. 359302)

Antigen Details

Structure: Integrin alpha chain family, type I membrane protein, alpha chain of heterodimeric integrin receptor, 170 kD; associates with CD29 to form collagen, laminin receptor
Distribution: Broadly expressed on many cell types including B cells, monocytes, platelets, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts
Function: With CD29; binds collagen and laminin
Ligand/Receptor: Forms heterodimer with integrin β1 (CD29) which is a receptor for laminin and collagen
Biology Area: Immunology, Innate Immunity
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Kaplan C, et al. 1991. Br. J. Haematol. 78:425.
2. Kiefel V, et al. 1991. Vox Sang. 60:244.
3. Nieuwenhuis HK, et al. 1985. Nature 318:470.
4. Takada Y and Helmer ME. 1989. J. Cell Biol. 109:397.
Gene ID: 3673 View all products for this Gene ID
UniProt: View information about CD49b on UniProt.org

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