FITC anti-human CD49b Antibody
- 产品名称：
- FITC anti-human CD49b Antibody
- 产品类别：
- 抗体
- 产品编号：
- 359305
- 产品应用：
- 359305
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1344 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- HT1080 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
- Application Notes
Additional reported applications (for the relevant formats of this clone) include: in vitro blocking activity1,2, immunoprecipitation3, and ELISA4.?
- Application References
(PubMed link indicates BioLegend citation) -
- Hirsch MS, et al. 1997. Dev. Dyn. 210:249. (Block)
- Sawhney RS, et al. 2006. J. Biol. Chem. 281:8497. (Block)
- Lee SA, et al. 2009. Carcinogensis. 30:1872. (IP)
- Z?rate S, et al. 2004. J. Virol. 78:10839. (ELISA)
- Product Citations
-
- Morad G, et al. 2020. International Journal of Molecular Sciences. 21(11):3851. PubMed
- Glehr G, et al. 2022. Front Immunol. 13:1011040. PubMed
- Lin JR et al. 2018. eLife. 7 pii: e31657. PubMed
- OConnor RA, et al. 2021. OncoImmunology. 10(1):1940675. PubMed
- RRID
- AB_2562530 (BioLegend Cat. No. 359305) AB_2562531 (BioLegend Cat. No. 359306)
- Structure
- Integrin alpha chain family, type I membrane protein, alpha chain of heterodimeric integrin receptor, 170 kD; associates with CD29 to form collagen, laminin receptor
- Distribution
-
Broadly expressed on many cell types including B cells, monocytes, platelets, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts
- Function
- With CD29; binds collagen and laminin
- Ligand/Receptor
- Forms heterodimer with integrin β1 (CD29) which is a receptor for laminin and collagen
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Kaplan C, et al. 1991. Br. J. Haematol. 78:425.
2. Kiefel V, et al. 1991. Vox Sang. 60:244.
3. Nieuwenhuis HK, et al. 1985. Nature 318:470.
4. Takada Y and Helmer ME. 1989. J. Cell Biol. 109:397.
- Gene ID
- 3673 View all products for this Gene ID
- UniProt
- View information about CD49b on UniProt.org
