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Purified anti-Connexin 43, 1-20 Antibody
产品名称:
Purified anti-Connexin 43, 1-20 Antibody
产品类别:
抗体
产品编号:
849901
产品应用:
849901
[价格]
规格 价格 库存
25µg ¥ 1416 1

产品详情

Product Details

Verified Reactivity
Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
A peptide corresponding to amino acids 1-20 of Connexin 43
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 to 5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Pollmann MA, et al. 2005. Breast Cancer Res. 7(4):R522 (WB)
  2. Kozoriz MG, et al. 2010. J Neuropathol Exp Neurol. 69(2): 196 (WB)
  3. Maass K, et al. 2007. Circ Res. 101(12):1283 (WB)
  4. Gellhaus A, et al. 2010. J Cell Biochem. 110(1):129 (WB)
  5. Oxford EM, et al. 2007 Circ Res. 101(7): 703 (WB)
RRID
AB_2715866 (BioLegend Cat. No. 849901) AB_2715867 (BioLegend Cat. No. 849902)

Antigen Details

Structure
Connexin 43 (GJA1) is a 382 amino acid protein with a molecular mass of 43 kD.
Distribution

Tissue distribution: expressed in most tissues, enriched in brain, endocrine, muscle, bone marrow, immune system, ovaries, testes, heart and skin.
Cellular distribution: plasma membrane, cytosol, mitochondria, golgi apparatus, cytoskeleton and endoplasmic reticulum membrane.

Function
Connexin 43 plays a role in cell-to-cell communication by forming channels, or gap junctions between cells. It allows for the transport of nutrients, charged particles (ions), and other small molecules that carry necessary communication signals between cells.
Biology Area
Cell Adhesion, Cell Biology
Molecular Family
Gap Junction Proteins
Antigen References

1. Grek CL, et al. 2016. Cancer Lett. 374(1):117
2. Lilly E, et al. 2016. Semin Cell Dev Biol. 50:4
3. Michela P, et al. 2015. Eur J Pharmacol. 768:71

Gene ID
2697 View all products for this Gene ID
UniProt
View information about Connexin 43 1-20 on UniProt.org

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