Purified anti-CD49C (Integrin α3) Antibody
- 产品名称：
- Purified anti-CD49C (Integrin α3) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 865201
- 产品应用：
- 865201
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- The P1B5 monoclonal antibody was generated against human HT1080 cells.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-F - Quality tested
FC, ICC - Verified
IP - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 - 5.0 ?g/ml is suggested. For flow cytometric staining, the suggested use of this reagent is between 1.0 - 10 ?g per million cells in 100 ?l volume. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody recognizes the a3 subunit.
- Application References
(PubMed link indicates BioLegend citation) -
- Wayner EA and Hoffstrom BG. 2007. Methods. Enzymol. 426:117.
- Wayner EA, et al. 1993. J Cell Biol. 121:1141. (IP)
- Carter WG, et al. 1990. J Cell Biol. 110:1387-404 (IP)
- Wayner EA and Carter WG. 1987. J Cell Biol. 105:1873. (IP)
- RRID
- AB_2810769 (BioLegend Cat. No. 865201) AB_2810770 (BioLegend Cat. No. 865202)
- Structure
- CD49c is a 150 kD type I transmembrane glycoprotein.
- Distribution
-
Cellular distribution: Plasma membrane.
Tissue distribution: Endothelial cells, epithelial cells, and dermal fibroblast.
- Function
- CD49c plays a role in cell-cell and cell-matrix adhesion.
- Ligand/Receptor
- Kalinin, collagen, laminin-1, laminin-5 and entactin, fibronectin
- Cell Type
- Endothelial cells, Epithelial cells, Fibroblasts
- Biology Area
- Cell Biology, Neuroscience, Signal Transduction, Synaptic Biology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Gene ID
- 3675 View all products for this Gene ID
- UniProt
- View information about CD49C on UniProt.org
