PE anti-mouse CD22 Antibody
- 产品名称：
- PE anti-mouse CD22 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 126111
- 产品应用：
- 126111
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Product Citations
-
- Aires V, et al. 2021. Front Immunol. 12:684430. PubMed
- Oswald DM, et al. 2020. Glycoconj J. 37:395. PubMed
- Graf R et al. 2019. Cell reports. 26(5):1098-1103 . PubMed
- RRID
- AB_2561631 (BioLegend Cat. No. 126111) AB_2561632 (BioLegend Cat. No. 126112)
- Structure
- 130-150 kd type 1 transmembrane glycoprotein. It is a member of the Siglec family and Ig superfamily.
- Distribution
-
CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells.
- Function
- B cell signaling and adhesion.
- Interaction
- Associates with SHP-1, Syk, Lck, Lyn and others.
- Cell Type
- B cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Symington FW et al. 1982. Immunogenetics 16:381
2. Erickson LD et al. 1996. Int Immunol 8:1121
3. Doody GM et al. 1995. Science 269:242
- Gene ID
- 12483 View all products for this Gene ID
- UniProt
- View information about CD22 on UniProt.org
