FITC anti-mouse CD22 Antibody
- 产品名称：
- FITC anti-mouse CD22 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 126105
- 产品应用：
- 126105
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
- Product Citations
-
- Enterina JR, et al. 2022. Cell Rep. 38:110512. PubMed
- Hegde S, et al. 2020. Cancer Cell. 37(3):289-307. PubMed
- Li H, et al. 2020. Nature. 584:274. PubMed
- RRID
- AB_1089007 (BioLegend Cat. No. 126105) AB_2244414 (BioLegend Cat. No. 126106)
- Structure
- 130-150 kd type 1 transmembrane glycoprotein. It is a member of the Siglec family and Ig superfamily.
- Distribution
-
CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells.
- Function
- B cell signaling and adhesion.
- Interaction
- Associates with SHP-1, Syk, Lck, Lyn and others.
- Cell Type
- B cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Symington FW et al. 1982. Immunogenetics 16:381
2. Erickson LD et al. 1996. Int Immunol 8:1121
3. Doody GM et al. 1995. Science 269:242
- Gene ID
- 12483 View all products for this Gene ID
- UniProt
- View information about CD22 on UniProt.org
