Alexa Fluor® 647 anti-mouse CD22 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1488	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested
IHC-F, 3D IHC?- Verified

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 10⁶ cells in 100 ?l volume. For immunohistochemistry, a concentration range of 2.5 - 5 ?g/ml is suggested.?For 3D immunohistochemistry on formalin-fixed tissues, a concentration of 5.0 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses

Excitation Laser

Red Laser (633 nm)

Product Citations

Enterina JR, et al. 2022. Cell Rep. 38:110512. PubMed
Cao A, et al. 2018. Nat Commun. 9:3288. PubMed
Smith LK, et al. 2021. Elife. 10:. PubMed
Wen T, et al. 2012. J Immunol. 188:1075. PubMed

RRID

AB_2074574 (BioLegend Cat. No. 126107) AB_2074573 (BioLegend Cat. No. 126108)

Antigen Details

Structure: 130-150 kd type 1 transmembrane glycoprotein. It is a member of the Siglec family and Ig superfamily.
Distribution: CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells.
Function: B cell signaling and adhesion.
Interaction: Associates with SHP-1, Syk, Lck, Lyn and others.
Cell Type: B cells
Biology Area: Immunology
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Symington FW et al. 1982. Immunogenetics 16:381
2. Erickson LD et al. 1996. Int Immunol 8:1121
3. Doody GM et al. 1995. Science 269:242
Gene ID: 12483 View all products for this Gene ID
UniProt: View information about CD22 on UniProt.org

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