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Purified anti-rat CD147 Antibody
产品名称:
Purified anti-rat CD147 Antibody
产品类别:
抗体
产品编号:
204601
产品应用:
204601
[价格]
规格 价格 库存
100µg ¥ 1416 1

产品详情

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
T blasts from a mixed lymphocyte reaction
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F, WB - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections1 and Western blotting2.

Application References

(PubMed link indicates BioLegend citation)
  1. Glenn M, et al. 1995. Circulation 92:1919. (IHC)
  2. Betsuyaku T, et al. 2003. Am. J. Respir. Cell Mol. Biol. 28:600. (WB)
RRID
AB_1186183 (BioLegend Cat. No. 204601)

Antigen Details

Structure
Single chain type I transmembrane 58 kd heavily glycosylated protein. N terminal extracellular part consists of two C2 type Ig-like domains which are highly glycosylated. Recently reported: isoform with an additional membrane-distal Ig-like domain.
Distribution

CD147 is expressed at varying levels in many cells types, including haematopoietic, epithelial, and endothelial cells. Expressed on immature thymocytes and at varying levels on spleen cells , bone marrow cells and macrophages.

Function
CD147 is implicated in multiple functions, such as matrix metalloproteinase induction, cell adhesion, retinal cell development, HIV attachment, embryonic development and T cell activation.
Ligand/Receptor
cyclophilin
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Glenn M, et al. 1995. Circulation 92:1919.
2. Betsuyaku T, et al. 2003. Am. J. Respir. Cell Mol. Biol. 28:600.

Gene ID
25246 View all products for this Gene ID
UniProt
View information about CD147 on UniProt.org

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