APC anti-rat CD11b/c Antibody
- 产品名称：
- APC anti-rat CD11b/c Antibody
- 产品类别：
- 抗体
- 产品编号：
- 201809
- 产品应用：
- 201809
- Verified Reactivity
- Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Rat peritoneal macrophages.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- 0.2 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections1,2, immunoprecipitation3, in vivo and in vitro blocking of C3bi binding3,4.
- Application References
(PubMed link indicates BioLegend citation) -
- Whiteland JL, et al. 1995. J. Histochem. Cytochem. 43:313. (IHC)
- Milligan CE, et al. 1991. J. Comp. Neurol. 314:125. (IHC)
- Robinson AP, et al. 1986. Immunology 57:239. (Block)
- Issekutz SE, et al. 1992. Immunology 76:655. (Block)
- Muehlbauer SM, et al. Am. J Pathol. 177:735. (FC) PubMed
- Thomas RA. et al. 2009. J Pharmacol Toxicol Methods. 60:263. PubMed
- Takeda Y, et al. 2011. Immunobiology. 216:1094. PubMed
- Furuhashi K, et al. 2013. J Am Soc Nephrol. PubMed
- Cheng HY, et al. 2013. Cytotherapy. 1465:608. PubMed
- Product Citations
-
- Thomas R, et al. 2009. J Pharmacol Toxicol Methods. 60:263. PubMed
- Furuhashi K, et al. 2013. J Am Soc Nephrol. 24:587. PubMed
- Orsi M, et al. 2021. Frontiers in Immunology. 12:666107. PubMed
- Choi JH, et al. 2021. J Neuroinflammation. 18:240. PubMed
- Schwarz J 2015. J Vis Exp. 99: 52537. PubMed
- Lin ZH, et al. 2018. Front Cell Neurosci. 0.729861111. PubMed
- Li Y, et al. 2021. Stem Cell Res Ther. 12:358. PubMed
- Cheng H, et al. 2014. Cytotherapy. 16:369. PubMed
- Hou J, et al. 2017. Mol Med Rep. 16:1502. PubMed
- Takeda Y, et al. 2011. Immunobiology. 216:1094. PubMed
- Wyatt‐Johnson SK et al. 2018. Frontiers in neurology. 0.819444444 . PubMed
- McCarthy C, et al. 2014. PLoS One. 9:95762. PubMed
- Ge Q, et al. 2018. Mol Med Rep. 17:1667. PubMed
- Guo J, et al. 2018. Int J Mol Med. 41:1976. PubMed
- Gorr MW, et al. 2020. Physiol Rep. 8:e14344. PubMed
- Yin J, et al. 2016. Am J Physiol Cell Physiol. 310: C41 - C53. PubMed
- Morishita K, et al. 2015. Am J Physiol Gastrointest Liver Physiol. 309: G202-G208. PubMed
- RRID
- AB_313995 (BioLegend Cat. No. 201809)
- Structure
- Integrin family member
- Distribution
-
Monocytes, granulocytes, macrophages, dendritic cells
- Function
- Receptor for C3bi
- Ligand/Receptor
- Complement C3bi
- Cell Type
- Dendritic cells, Granulocytes, Macrophages, Monocytes
- Biology Area
- Cell Biology, Complement, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Robinson AP, et al. 1986. Immunology 57:239.
2. Barcaly AN. 1981 Immunology 42:593.
- Gene ID
- 25021 View all products for this Gene ID 499271 View all products for this Gene ID
- UniProt
- View information about CD11b CD11c on UniProt.org
