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APC anti-rat CD200 Antibody
产品名称:
APC anti-rat CD200 Antibody
产品类别:
抗体
产品编号:
204809
产品应用:
204809
[价格]
规格 价格 库存
100µg ¥ 2556 1

产品详情

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
Concentration
0.2 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

1. Dick, A.D., et al. 2001. Invest Ophthalmol. Vis. Sci. 42:170.

RRID
AB_2890731 (BioLegend Cat. No. 204809)

Antigen Details

Structure
A 47kD (thymus) or 41-kD (brain) type I membrane glycoprotein member of the Ig supergene family. CD200 molecule contains two extracellular Ig-like domains, an Ig V-like, and an Ig C-like domain.
Distribution

CD200 is expressed on B cells, a subset of T cells, thymocytes, follicular dendritic cells, neurons, vascular endothelium, and some smooth muscle.

Function
The interaction of CD200 with CD200 receptor provide a potent costimulatory T-cell signal in the presence of TCR signaling, stimulate macrophages, and inhibit mast cell degranulation.
Ligand/Receptor
CD200 receptor
Cell Type
B cells, Dendritic cells, Endothelial cells, Neurons, T cells, Thymocytes
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. McMaster WR, et al. 1979. Eur. J. Immunol. 9:426
2. Barclay A. N, et al. 1981. Immunology. 44:727
3. Bukovsky A, et al. 1984. Immunol. 52:631
4. Borriello F, et al. 1997. J. Immunol. 158:4548
5. Gorczynski R. M, et al. 1999. J. Immunol. 163:1654
6. Gorczynski L, et al. 1999. J. Immunol. 162:774

Gene ID
24560 View all products for this Gene ID
UniProt
View information about CD200 on UniProt.org

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