PE anti-human CD200 (OX2) Antibody
- 产品名称：
- PE anti-human CD200 (OX2) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 329205
- 产品应用：
- 329205
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1320 |
1 |
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported applications (for the relevant formats) include: immunohistochemistry of formalin-fixed paraffin-embedded sections1 and acetone-fixed frozen sections2, and blocking of CD200 interaction with CD200R.
- Application References
(PubMed link indicates BioLegend citation) -
- Patel GK, et al. 2012. J. Invest. Dermatol. 132:401. (IHC)
- Wright GJ, et al. 2001. Immunology 102:173. (IHC)
- Foster-Cuevas M, et al. 2004. J. Virol. 78:7667. (FC)
- Product Citations
-
- Pino M, et al. 2022. Nat Commun. 13:5055. PubMed
- Harper J, et al. 2022. J Clin Invest. . PubMed
- Byrareddy S, et al. 2015. PLoS One. 10: e0140689. PubMed
- Bojic S, et al. 2018. Stem Cells. 36:1723. PubMed
- Harper JL, et al. 2020. Nat Med. 519:26. PubMed
- Vattulainen M, et al. 2019. Stem Cell Res Ther. 10:236. PubMed
- RRID
- AB_1027677 (BioLegend Cat. No. 329205) AB_2074065 (BioLegend Cat. No. 329206)
- Structure
- Immunoglobulin superfamily
- Distribution
-
T cells, neurons, endothelium
- Function
- Costimulates T cell proliferation
- Receptors
- CD200R
- Cell Type
- Endothelial cells, Neurons, T cells
- Biology Area
- Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- CD Molecules
- Antigen References
-
1. Wright GJ, et al. 2001. Immunol. 102:173.
2. Foster-Cuevas M, et al. 2004. J. Virol. 78:7667.
3. Mason D, et al. 2002. ed. Leukocyte Typing VII. New York:Oxford Univ. Press.
4. Broderick C, et al. 2002. Am. J. Pathol. 161:1669.
- Regulation
- Induces a downregulation of macrophage activity
- Gene ID
- 4345 View all products for this Gene ID
- UniProt
- View information about CD200 on UniProt.org
