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首页 > 抗体蛋白 > 抗体
PE anti-rat CD45 Antibody
产品名称：
PE anti-rat CD45 Antibody
产品类别：
抗体
产品编号：
202207
产品应用：
202207
[价格]
规格 价格 库存
50µg ￥ 1692 1

产品详情

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Enriched glycoprotein fraction from Wistar rat thymocytes
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation1, immunofluorescence microscopy (acetone fixed, ammonium-thiocyanate separated epidermal sheets)2, immunohistochemistry of acetone3-, isopentane-4, PLP5-, and n-hexane6 fixed frozen sections and paraffin-embedded sections7,8, and partial inhibition of NK cell lysis of syngeneic tumor cell lines1.

Application References

(PubMed link indicates BioLegend citation)
  1. Giezeman-Smits KM, et al. 1999. J. Immunol. 163:71. (IP)
  2. Elbe A, et al. 1994. J. Invest. Dermatol. 102:74. (IF)
  3. Kouwenhoven E, et al. 2001. Kidney Int. 59:1142. (IHC)
  4. Martin A, et al. 1995 Clin. Exp. Immunol. 22:283. (IHC)
  5. Sayegh MH, et al. 1995 J. Exp. Med. 181:186. (IHC)
  6. Morioka Y, et al. 2000. Kidney Int. 60:2192. (IHC)
  7. Ng YY, et al. 2005. Kidney Int. 94:S83. (IHC-P)
  8. Huang XR, et al. 2003. JASN. 14:1738. (IHC-P)
Product Citations
  1. Basham HK, et al. 2021. Int J Mol Sci. 22:. PubMed
  2. Yan H, et al. 2020. Adv Sci (Weinh). 7:1903516. PubMed
  3. Chen M, et al. 2021. Bioact Mater. 1.591666667. PubMed
  4. Fu Y, et al. 2020. Mol Ther. 1214:28. PubMed
  5. Choi JH, et al. 2021. J Neuroinflammation. 18:240. PubMed
  6. Liu J, et al. 2022. BMC Genomics. 23:425. PubMed
  7. Jiang T, et al. 2022. Tissue Eng Regen Med. . PubMed
  8. Hendawy H, et al. 2021. Cells. 10:. PubMed
  9. Yamada S, et al. 2021. J Tissue Eng. 12:20417314211019375. PubMed
  10. Hamanaka S, et al. 2011. PLoS One. 6:e22008. PubMed
  11. Chou PR, et al. 2020. Int J Med Sci. 17:354. PubMed
  12. Faidah M, et al. 2017. Adv Clin Exp Med. 26:1171. PubMed
  13. Zimmerman KA, et al. 2019. J Am Soc Nephrol. 30:767. PubMed
  14. Li Y, et al. 2021. Stem Cell Res Ther. 12:358. PubMed
  15. Shin EY, et al. 2018. J Am Heart Assoc. 7:e006949. PubMed
  16. Zimmerman KA, et al. 2021. Am J Physiol Renal Physiol. 321:F162. PubMed
  17. Pele T, et al. 2021. Int J Mol Sci. 22:. PubMed
  18. Liang H, et al. 2021. J Neuroinflammation. 18:40. PubMed
  19. Cizkova D, et al. 2014. Sci Rep. 4:7514. PubMed
  20. Feng Q et al. 2018. The Journal of physiology. 597(3):781-798 . PubMed
RRID
AB_314006 (BioLegend Cat. No. 202207)

Antigen Details

Structure
Protein tyrosine phosphatase, type I transmembrane protein, 180-220 kD (multiple isoforms and differential glycosylation)
Distribution

All hematopoietic cells except erythrocytes and platelets

Function
T cell receptor and B cell receptor signal transduction
Ligand/Receptor
Galectin-1, CD2, CD3, CD4
Biology Area
Cell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Molecular Family
CD Molecules
Antigen References

1. Sunderland CA, et al. 1979. Eur. J. Immunol. 9:155.
2. Woolett GR, et al. 1985. Eur. J. Immunol.. 15:168.

Gene ID
24699 View all products for this Gene ID
UniProt
View information about CD45 on UniProt.org

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