Purified anti-RRM1 Antibody
- 产品名称:
- Purified anti-RRM1 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 937101
- 产品应用:
- 937101
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Partial recombinant human RRM1 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB -?Quality tested
ICC -?Verified
- Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.5?- 1.0??g/mL.?For immunocytochemistry, a concentration range of 1.0?- 2.0?μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
A minor 37kD band was detected by the clone during western blot product development testing. This band was also detected using a control antibody that was generated with a separate RRM1 immunogen; we believe this band represents a minor RRM1 degradation product.
When tested for ICC on HeLa cells fixed with PFA and permeabilized with Triton X-100, this clone failed to stain RRM1. We therefore do not recommend this fixation-permeabilization step when using this clone for ICC.
- RRID
- AB_2861122 (BioLegend Cat. No. 937101) AB_2861123 (BioLegend Cat. No. 937102)
- Structure
- RRM1 is a 792 amino acid protein with a predicted molecular weight of 90 kD.
- Distribution
-
Cytosol
- Biology Area
- Cell Biology, Cell Cycle/DNA Replication, DNA Repair/Replication
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
- Bepler G, et al. 2006. J Clin Oncol. 24:4731.
- Zheng Z, et al. 2007. N Engl J Med. 356:800.
- Ceppi P, et al. 2006. Ann Oncol. 17:1818.
- Gene ID
- 6240 View all products for this Gene ID
- UniProt
- View information about RRM1 on UniProt.org