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Purified anti-RRM1 Antibody
产品名称:
Purified anti-RRM1 Antibody
产品类别:
抗体
产品编号:
937101
产品应用:
937101
[价格]
规格 价格 库存
25µg ¥ 1212 1

产品详情

Product Details

Verified Reactivity
Human, Mouse
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Partial recombinant human RRM1 protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB -?Quality tested
ICC -?Verified

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.5?- 1.0??g/mL.?For immunocytochemistry, a concentration range of 1.0?- 2.0?μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

A minor 37kD band was detected by the clone during western blot product development testing. This band was also detected using a control antibody that was generated with a separate RRM1 immunogen; we believe this band represents a minor RRM1 degradation product.

When tested for ICC on HeLa cells fixed with PFA and permeabilized with Triton X-100, this clone failed to stain RRM1. We therefore do not recommend this fixation-permeabilization step when using this clone for ICC.

RRID
AB_2861122 (BioLegend Cat. No. 937101) AB_2861123 (BioLegend Cat. No. 937102)

Antigen Details

Structure
RRM1 is a 792 amino acid protein with a predicted molecular weight of 90 kD.
Distribution

Cytosol

Biology Area
Cell Biology, Cell Cycle/DNA Replication, DNA Repair/Replication
Molecular Family
Enzymes and Regulators
Antigen References
  1. Bepler G, et al. 2006. J Clin Oncol. 24:4731.
  2. Zheng Z, et al. 2007. N Engl J Med. 356:800.
  3. Ceppi P, et al. 2006. Ann Oncol. 17:1818.
Gene ID
6240 View all products for this Gene ID
UniProt
View information about RRM1 on UniProt.org

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