Purified anti-SOD1 Antibody
- 产品名称:
- Purified anti-SOD1 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 850701
- 产品应用:
- 850701
- Verified Reactivity
- Human, Mouse, Rat, Drosophila
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full-length human SOD1 expressed in 293T cells transfected with human SOD1 expression vector.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB -?Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Reactivity to Drosophila was only verified with the purified format.
- Additional Product Notes
For Western blotting, the suggested use of this reagent is 1 - 5 ?g/ml in human, mouse, and rat and 0.5 - 10 ?g/ml in Drosophila.
- RRID
- AB_2716015 (BioLegend Cat. No. 850701) AB_2716016 (BioLegend Cat. No. 850702)
- Structure
- SOD1 is a homodimeric β-barrel protein that contains an intramolecular disulfide bond and a binuclear Cu/Zn site in each subunit. SOD1 monomers have an apparent molecular weight of ~16 kD.
- Distribution
-
Tissue sources: Ubiquitously expressed. ?
Cellular distribution: Cytosol, mitochondrion, peroxisome and nucleus.
- Function
- SOD1 converts harmful superoxide radicals in the body to oxygen and hydrogen peroxide.
- Interaction
- UBC, CCS, PRDX1, HSPA4
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
1. Lee S, Kim HJ. 2015.?Exp. Neurobiol.?24(1):1-7.
2. Tafuri F,?et al. 2015. Front Cell Neurosci.?9: 336.
3. Palomo, GM, Manfredi G. 2015.?Brain Res.?1607:36-46.
4. Rosen DR,?et al.?1993.?Nature?362 (6415):59-62.
- Gene ID
- 6647 View all products for this Gene ID
- UniProt
- View information about SOD1 on UniProt.org