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Purified anti-SOD1 Antibody
产品名称:
Purified anti-SOD1 Antibody
产品类别:
抗体
产品编号:
850701
产品应用:
850701
[价格]
规格 价格 库存
25µg ¥ 1272 1

产品详情

Product Details

Verified Reactivity
Human, Mouse, Rat, Drosophila
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Full-length human SOD1 expressed in 293T cells transfected with human SOD1 expression vector.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB -?Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Reactivity to Drosophila was only verified with the purified format.

Additional Product Notes

For Western blotting, the suggested use of this reagent is 1 - 5 ?g/ml in human, mouse, and rat and 0.5 - 10 ?g/ml in Drosophila.

RRID
AB_2716015 (BioLegend Cat. No. 850701) AB_2716016 (BioLegend Cat. No. 850702)

Antigen Details

Structure
SOD1 is a homodimeric β-barrel protein that contains an intramolecular disulfide bond and a binuclear Cu/Zn site in each subunit. SOD1 monomers have an apparent molecular weight of ~16 kD.
Distribution

Tissue sources: Ubiquitously expressed. ?
Cellular distribution: Cytosol, mitochondrion, peroxisome and nucleus.

Function
SOD1 converts harmful superoxide radicals in the body to oxygen and hydrogen peroxide.
Interaction
UBC, CCS, PRDX1, HSPA4
Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
Enzymes and Regulators
Antigen References

1. Lee S, Kim HJ. 2015.?Exp. Neurobiol.?24(1):1-7.
2. Tafuri F,?et al. 2015. Front Cell Neurosci.?9: 336.
3. Palomo, GM, Manfredi G. 2015.?Brain Res.?1607:36-46.
4. Rosen DR,?et al.?1993.?Nature?362 (6415):59-62.

Gene ID
6647 View all products for this Gene ID
UniProt
View information about SOD1 on UniProt.org

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