Alexa Fluor® 594 anti-SATB1 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 4440	1

Product Details

Verified Reactivity: Human, Mouse
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: Full length recombinant human SATB1 (NP_002962) produced in HEK293T cells.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 594 under optimal conditions.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 0.1 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 594 has an excitation maximum of 590 nm, and a maximum emission of 617 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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RRID: AB_2566180 (BioLegend Cat. No. 676104)

Structure: Homodimer. Canonical sequence contains 763 amino acids, predicted molecular weight of 86 kD. Isoform contains 795 amino acids, predicted molecular weight of 89 kD.
Distribution: Nucleus matrix. Nucleus. Promyelocytic leukemia nuclear bodies (SUMOylated).
Function: SATB1 recruits chromatin remodeling factors to regulate chromatin-loop structure and gene transcription. It is an important silencing factor for initiating the Xist RNA-mediated X inactivation in mammals.
Interaction: CUX1, CtBP1, PCAF, SUMOylated PML, HDAC1 and HIV-1 Tat, DYNLT2, POLR2J2, EP300, special AT-rich DNA sequences (consensus SATB1-binding sequence, CSBS).
Biology Area: Cell Biology, Immunology, Transcription Factors
Antigen References: 1. Agrelo R, et al. 2009. Dev. Cell. 16:507.
2. Han HJ, et al. 2008. Nature. 452:187.
3. Cai S, et al. 2006. Nature Genet. 38:1278.
4. Pavan Kumar, P, et al. 2006. Mol. Cell. 22:231.
5. Fujii Y, et al. 2003. Microbiol. Immunol. 47:803.
6. Yasui, D, et al. 2002. Nature. 419:641.
Gene ID: 6304 View all products for this Gene ID
UniProt: View information about SATB1 on UniProt.org