Purified anti-p62 (SQSTM1) Antibody
- 产品名称:
- Purified anti-p62 (SQSTM1) Antibody
- 产品类别:
- 抗体
- 产品编号:
- 937201
- 产品应用:
- 937201
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Full-length recombinant human SQSTM1 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
ICC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 2 - 5 μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
When this clone was tested for western blot, a non-specific band close to the predicted molecular weight of p62 was observed. This protein was also detected in O95A2 immunoprecipitates. We therefore do not recommend this clone for western blot or immunoprecipitation applications.
This clone was tested for ICC using 4% PFA-fixed HeLa cells permeabilized with Triton X-100 or methanol. Both methods were compatible with p62 staining.
- RRID
- AB_2861124 (BioLegend Cat. No. 937201) AB_2861125 (BioLegend Cat. No. 937202)
- Structure
- p62 is a 440 amino acid protein with a predicted molecular weight of 47 kD.
- Distribution
-
Vesicles and Cytosol/Ubiquitously expressed
- Function
- Autophagy
- Biology Area
- Cell Biology, Neuroscience, Protein Misfolding and Aggregation
- Molecular Family
- Adaptor Proteins
- Antigen References
-
- Komatsu M, et al. 2007. Cell. 6:1149.
- Bj?rk?y G, et al. 2006. Autophagy. 2:138.
- Bj?rk?y G, et al. 2005. J Cell Biol. 171:603.
- Gene ID
- 8878 View all products for this Gene ID
- UniProt
- View information about p62 on UniProt.org