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Brilliant Violet 605™ anti-human CD27 Antibo
产品名称:
Brilliant Violet 605™ anti-human CD27 Antibo
产品类别:
抗体
产品编号:
302829
产品应用:
302829
[价格]
规格 价格 库存
25tests ¥ 2580 1

产品详情

Product Details

Verified Reactivity
Human, Cynomolgus, Rhesus
Reported Reactivity
African Green, Baboon, Squirrel Monkey
Antibody Type
Monoclonal
Host Species
Mouse
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA).
Preparation
The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 605? under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Brilliant Violet 605? excites at 405 nm and emits at 603 nm. The bandpass filter 610/20 nm is recommended for detection, although filter optimization may be required depending on other fluorophores used. Be sure to verify that your cytometer configuration and software setup are appropriate for detecting this channel. Refer to your instrument manual or manufacturer for support. Brilliant Violet 605? is a trademark of Sirigen Group Ltd.


Learn more about Brilliant Violet?.

This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.
Excitation Laser
Violet Laser (405 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
  2. Correia DV, et al. 2011. Blood 118:992. (FC) PubMed
Product Citations
  1. Wheatley A, et al. 2016. Sci Rep. 6: 26478. PubMed
  2. Yu B, et al. 2021. Cell. 184(7):1790-1803.e17. PubMed
  3. Townsley SM, et al. 2021. Cell Host Microbe. 29(4):564-578.e9. PubMed
  4. Stadinski B, et al. 2016. Nat Immunol. 10.1038/ni.3491. PubMed
  5. Gros A, et al. 2016. Nat Med. 10.1038/nm.4051. PubMed
  6. Mukhamedova M, et al. 2021. Immunity. 54(4):769-780.e6. PubMed
  7. Jennewein MF, et al. 2021. Cell Reports. 36(2):109353. PubMed
  8. Arif S, et al. 2021. Front Immunol. 12:675746. PubMed
  9. Mor M, et al. 2020. bioRxiv. . PubMed
  10. Calascibetta F, et al. 2016. J Virol. 90: 7541 - 7551. PubMed
  11. Sutton HJ, et al. 2021. Cell Reports. 34(6):108684. PubMed
  12. Cartwright E, et al. 2014. J Immunol. 192:4666. PubMed
  13. Ollé Hurtado M, et al. 2019. PLoS One. 14:e0216373. PubMed
  14. Juno JA, et al. 2020. Nat Med. 26:1428. PubMed
  15. Tardif V, et al. 2019. Nat Commun. 10:823. PubMed
  16. Tan J, et al. 2021. Sci Transl Med. 13: . PubMed
  17. Nguyen THO, et al. 2021. Immunity. 54:1066. PubMed
  18. Cohen KW, et al. 2021. Cell Reports Medicine. 2(7):100354. PubMed
  19. Medvec AR, et al. 2018. Mol Ther Methods Clin Dev. 8:65. PubMed
  20. Punik J, et al. 2021. Cell Reports. 35(13):109320. PubMed
  21. Amodio D, et al. 2018. J Immunol. 200:538. PubMed
  22. Wong G, et al. 2016. J Immunol. 197: 1642 - 1649. PubMed
  23. Pillet S, et al. 2016. Clin Immunol. 168:72-87. PubMed
  24. Townsley SM, et al. 2021. STAR Protocols. 2(3):100771. PubMed
  25. Liu Y, et al. 2019. Nat Commun. 10:324. PubMed
  26. Li D, et al. 2020. Immunohorizons. 0.661805556. PubMed
  27. Neu KE, et al. 2019. J Clin Invest. 129:93. PubMed
  28. Mor M, et al. 2021. PLoS Pathog. 17:e1009165. PubMed
  29. Seydoux E, et al. 2020. Immunity. 53:98. PubMed
RRID
AB_11204431 (BioLegend Cat. No. 302829) AB_2561450 (BioLegend Cat. No. 302830)

Antigen Details

Structure
TNF-R superfamily, type I transmembrane glycoprotein, 50-55 kD
Distribution

Medullary thymocytes, T and B cell subsets, NK cells

Function
T cell costimulation
Ligand/Receptor
CD70
Cell Type
B cells, NK cells, T cells, Thymocytes, Tregs
Biology Area
Costimulatory Molecules, Immunology
Molecular Family
CD Molecules
Antigen References

1. Hintzen R, et al. 1994. Immunol. Today 15:307.
2. Agematsu K, et al. 1995. J. Immunol. 154:3627.

Gene ID
939 View all products for this Gene ID
UniProt
View information about CD27 on UniProt.org

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