Purified anti-Presenilin 1 (N terminus) Antibody (
- 产品名称:
- Purified anti-Presenilin 1 (N terminus) Antibody (
- 产品类别:
- 抗体
- 产品编号:
- 823404
- 产品应用:
- 823404
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- BioLegend's mouse anti-Presenilin 1 was raised against a portion of the n-terminal region of Presenilin 1 (RRSLGHPEP).
- Formulation
- Phosphate-buffered solution.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 1 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody is against the N-terminus of Presenilin 1 and detects the N-terminal fragment (NTF) generated from the proteolysis of the full-length protein (52kD).
- Application References
(PubMed link indicates BioLegend citation) -
- Mathews PM, et al. 2000. Mol Med. 6(10)
- Cohen RM, et al. 2013. J. Neurosci. 15:6245. (WB) PubMed
- Laudon H, et al. 2004. J Neurochem. 89:44-53
- Ahn K, et al. 2010. Proc Natl Acad Sci U S A. 107:21435
- Product Citations
-
- Bohl B, et al. 2022. Sci Adv. 8:eabl5792. PubMed
- Cohen R, et al. 2013. J Neurosci. 33:6245-6256. PubMed
- RRID
- AB_2734591 (BioLegend Cat. No. 823404) AB_2564868 (BioLegend Cat. No. 823401)