首页 > 抗体蛋白 > 抗体
Purified anti-Presenilin 1 (N terminus) Antibody (
产品名称:
Purified anti-Presenilin 1 (N terminus) Antibody (
产品类别:
抗体
产品编号:
823404
产品应用:
823404
[价格]
规格 价格 库存
25µL ¥ 1344 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
BioLegend's mouse anti-Presenilin 1 was raised against a portion of the n-terminal region of Presenilin 1 (RRSLGHPEP).
Formulation
Phosphate-buffered solution.
Preparation
The antibody was purified by affinity chromatography.
Concentration
1 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check your vial or your CoA to find the most accurate storage condition for this antibody.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody is against the N-terminus of Presenilin 1 and detects the N-terminal fragment (NTF) generated from the proteolysis of the full-length protein (52kD).

Application References

(PubMed link indicates BioLegend citation)
  1. Mathews PM, et al. 2000. Mol Med. 6(10)
  2. Cohen RM, et al. 2013. J. Neurosci. 15:6245. (WB) PubMed
  3. Laudon H, et al. 2004. J Neurochem. 89:44-53
  4. Ahn K, et al. 2010. Proc Natl Acad Sci U S A. 107:21435
Product Citations
  1. Bohl B, et al. 2022. Sci Adv. 8:eabl5792. PubMed
  2. Cohen R, et al. 2013. J Neurosci. 33:6245-6256. PubMed
RRID
AB_2734591 (BioLegend Cat. No. 823404) AB_2564868 (BioLegend Cat. No. 823401)

Antigen Details

Structure
Expected MW: 26 kD
Biology Area
Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation
Molecular Family
Secretases
Gene ID
5663 View all products for this Gene ID
UniProt
View information about Presenilin 1 NH2 terminus on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线