APC anti-human CD203c (E-NPP3) Antibody
- 产品名称：
- APC anti-human CD203c (E-NPP3) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 324609
- 产品应用：
- 324609
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1848 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- HEK-293 cells transfected with human E-NPP3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application References
(PubMed link indicates BioLegend citation) -
- Bühring HJ, et al. 1999. Blood 94:2343.
- Bühring HJ, et al. 2001. Blood 97:3303.
- Platz IJ, et al. 2001. Int. Arch. Allergy Immunol. 126:335.
- Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
- Gernez Y, et al. 2011. Int. Arch. Allergy Immunol. 154:318. (FC) PubMed
- Product Citations
-
- Siegel A, et al. 2013. J Allergy Clin Immunol. 132:1388. PubMed
- De Domenico E, et al. 2020. STAR Protoc. 1:100233. PubMed
- Sicklinger F, et al. 2021. J Clin Invest. 131:. PubMed
- Ebo D, et al. 2012. J Immunol Methods. 375:30. PubMed
- RRID
- AB_2099774 (BioLegend Cat. No. 324609) AB_2099773 (BioLegend Cat. No. 324610)
- Structure
- Transmembrane ectoenzyme family member involved in the hydrolysis of extracellular oligonucleotides, nucleoside phosphates, and NAD (possesses ATPase and ATP pyrophosphatase activity); reduced molecular weight is 130 and 150 kD, unreduced is 270 kD
- Distribution
-
Basophils and mast cells, highly expressed on activated basophils; secretory glands in endometrium and glioma cells are also positive
- Function
- Multifunctional ectoenzyme involved in the clearance of extracellular nucleotides
- Ligand/Receptor
- Substrates include nucleoside triphosphates, nucleoside diphosphates, cAMP, and NAD
- Cell Type
- Basophils, Mast cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Yano Y, et al. 2003. Int. J. Mol. Med. 12:763.
2. Andoh K, et al. 1999. Biochim. Biophys. Acta. 1446:213.
- Gene ID
- 5169 View all products for this Gene ID
- UniProt
- View information about CD203c on UniProt.org
