PE anti-human CD49e Antibody
- 产品名称：
- PE anti-human CD49e Antibody
- 产品类别：
- 抗体
- 产品编号：
- 328009
- 产品应用：
- 328009
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1608 |
1 |
- Verified Reactivity
- Human, Cynomolgus, Rhesus
- Reported Reactivity
- African Green, Baboon
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- U937 cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
Additional reported (for the relevant formats) applications include: immunohistochemical staining of acetone-fixed frozen sections, immunoprecipitation, and inhibition of a5 integrin mediated cell adhesion2. The LEAF? purified antibody (Endotoxin <0.1 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 328004).
- Application References
(PubMed link indicates BioLegend citation) -
- Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
- Orecchia A, et al. 2003. J. Cell Sci. 116:3479. (Block)
- Product Citations
-
- Frank N, et al. 2005. Cancer Res. 65:4320. PubMed
- Ferreira L, et al. 2016. Proc Natl Acad Sci U S A. 113: 5364 - 5369. PubMed
- Tabebordbar M, et al. 2021. Cell. 184:4919. PubMed
- Kawamoto E, et al. 2021. Biomedicines. 9:. PubMed
- RRID
- AB_893368 (BioLegend Cat. No. 328009) AB_2280539 (BioLegend Cat. No. 328010)
- Structure
- Integrin family, associates with integrin ?1 (CD29), 135 kD and 25 kD in reduced condition, 155 kD (unreduced)
- Distribution
-
Thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, some myeloid leukemia cells
- Function
- Adhesion, regulation of cell survival and apoptosis
- Ligand/Receptor
- Fibronectin, neural adhesion molecule L1
- Cell Type
- Endothelial cells, Leukemia, Lymphocytes, Mesenchymal Stem Cells, Osteoclasts, Thymocytes
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1.Tran Van Nhieu GT and Isberg RR. 1991. J. Biol. Chem. 266:24367.
2. Isaji T, et al. 2006.J. Biol. Chem. 281:33258.
- Gene ID
- 3678 View all products for this Gene ID
- UniProt
- View information about CD49e on UniProt.org
