FITC anti-human CD51 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25tests	￥ 1128	1

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Melonama cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation

The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.

Concentration

Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser

Blue Laser (488 nm)

Application References (PubMed link indicates BioLegend citation)

Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
Defilippi P, et al. 1991. J. Cell Biol. 114:855. PubMed
Burdick MM, et al. 2003. Am. J. Physiol.Cell Ph. 284:C977. PubMed
Grzeszkiewicz TM, et al. 2001. J. Biol. Chem. 276:21943.
Sonnenberg A, et al. 1990. J. Cell Biol. 110:2145. PubMed
Silverman AP, et al. 2008. J Mol Biol. 385:1064. PubMed
Khurana S, et al. 2013. Blood. 121:2587. PubMed

Product Citations

Silverman A, et al. 2008. J Mol Biol. 385:1064. PubMed
Arulmoli J, et al. 2016. Acta Biomater. 43:122-138. PubMed
Wang J, et al. 2016. Oncogene. 10.1038/onc.2016.299. PubMed
Lawrence M, et al. 2022. Sci Adv. 8:eabj8618. PubMed
Kenswil KJG, et al. 2021. Cell Stem Cell. 28(4):653-670.e11. PubMed
Goncharova V, et al. 2014. Stem Cells Trans Med. 3:229. PubMed
Sui X, et al. 2018. Cell Death Dis. 9:523. PubMed
Shlamkovich T, et al. 2020. BMC Biology. 16(1):92. PubMed
Fuhrmann A, et al. 2017. Biophys J. 112(4):736-745. PubMed
Malenica I, et al. 2021. Nat Commun. 12:5209. PubMed
Khurana S, et al. 2013. Blood. 121:2587. PubMed

RRID

AB_940558 (BioLegend Cat. No. 327907) AB_940560 (BioLegend Cat. No. 327908)

Antigen Details

Structure: Integrin, forms heterodimer with integrin β1 (CD29), β3 (CD61), β5, β6, or β8, 125 kD and 24 kD in reduced condition, 150 kD (unreduced)
Distribution: Endothelial cells, fibroblasts, macrophages, platelets, osteoclasts, neuroblastoma, melanoma, and hepatoma cells.
Function: Adhesion, angiogenesis
Ligand/Receptor: Vitronectin, von Willebrand factor, fibrinogen, thrombospondin, osteopontin, denatured collagen, fibronectin, laminin.
Cell Type: Endothelial cells, Fibroblasts, Macrophages, Mesenchymal Stem Cells, Osteoclasts, Platelets
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Stem Cells
Molecular Family: CD Molecules
Antigen References: 1. Nesbitt S, et al. 1993. J. Biol. Chem. 268:16737.
2. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication
Gene ID: 3685 View all products for this Gene ID
UniProt: View information about CD51 on UniProt.org

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