Ultra-LEAF™ Purified anti-human CD96 (TACTIL
- 产品名称：
- Ultra-LEAF™ Purified anti-human CD96 (TACTIL
- 产品类别：
- 抗体
- 产品编号：
- 338421
- 产品应用：
- 338421
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is <0.01 EU/?g of the protein (<0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
FA - Reported in the literature, not verified in house
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Additional reported applications include: block interaction of CD96 with PVR and functional assay
- Application References
(PubMed link indicates BioLegend citation) -
- Fuchs A, et al. 2004. J. Immunol. 172:3994
- Manes TD, et al. 2011. J. Immunol. 186:1763. PubMed
- RRID
- AB_2810529 (BioLegend Cat. No. 338421) AB_2810530 (BioLegend Cat. No. 338422)
- Structure
- 160 kD, type I transmembrane protein, Ig superfamily
- Distribution
-
NK cells, T cells (upregulated upon activation)
- Ligand/Receptor
- CD155 (PVR)
- Cell Type
- NK cells, T cells
- Biology Area
- Immunology, Innate Immunity, Inhibitory Molecules
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley & Sons Inc, Publication
2. Hosen N, et al. 2007. Proc. Natl. Acad. Sci. USA 104:11008
3. Gong J, et al. 2008. Clin. Exp. Immunol.
- Gene ID
- 10225 View all products for this Gene ID
- UniProt
- View information about CD96 on UniProt.org
