APC/Fire 750™ anti-mouse CD44 Antibody
- 产品名称：
- APC/Fire 750™ anti-mouse CD44 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 156003
- 产品应用：
- 156003
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Fire? 750 under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
* APC/Fire??750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
From in-house testing, this clone does not block IM7.?This clone has been used to induce dendrite formation in B cells.1
- Application References
(PubMed link indicates BioLegend citation) -
- Santos-Argumedo L,?et al.?1997.?Immunology.?90:147 (FC, Agonist)
- RRID
- AB_2910319 (BioLegend Cat. No. 156003) AB_2910319 (BioLegend Cat. No. 156004)
- Structure
- Variable splicing of CD44 gene generates many CD44 isoforms, 80-95 kD
- Distribution
-
All leukocytes, epithelial cells, endothelial cells, hepatocytes, mesenchymal cells
- Function
- Leukocyte attachment and rolling on endothelial cells, stromal cells and ECM
- Ligand/Receptor
- Hyaluronan, MIP-1β, fibronectin, collagen
- Cell Type
- Leukocytes, Epithelial cells, Endothelial cells, Mesenchymal cells, B cells
- Biology Area
- Immunology
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Barclay AN,?et al.?1997.?The Leukocyte Antigen FactsBook Academic Press.
- Haynes BF,?et al.?1991.?Cancer Cells?3:347.
- Goldstein LA,?et al.?1989.?Cell?56:1063.
- Mikecz K,?et al.?1995.?Nat. Med.?1:558.
- Hegde V,?et al.?2008.?J. Leukocyte Biol.?84:134.
- Liu T,?et al.?2009.?Biol. Direct?4:40.
- Gene ID
- 12505 View all products for this Gene ID
- UniProt
- View information about CD44 on UniProt.org
