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首页 > 抗体蛋白 > 抗体
APC/Cyanine7 anti-mouse CD11c Antibody
产品名称：
APC/Cyanine7 anti-mouse CD11c Antibody
产品类别：
抗体
产品编号：
117324
产品应用：
117324
[价格]
规格 价格 库存
100µg ￥ 3504 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Armenian Hamster
Immunogen
Mouse spleen dendritic cells
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography, and conjugated with APC/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is = 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application Notes

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9 (Alexa Fluor? 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Additional Product Notes
BioLegend is in the process of converting the name APC/Cy7 to APC/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our APC/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Granucci F, et al. 1997. J. Immunol. 159:1794.
  2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
  3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
  4. Ma XT, et al. 2006. Cancer Research 66:1169.
  5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
  6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
  7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
  8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
  9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
  10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
  11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
  12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
  13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
  14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
  15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
  16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
  17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
  18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
  19. Sakai F, et al. 2014. PLoS One. 9:105370. PubMed
  20. Gibbins JD, et al. 2014. Blood. 124:2953. PubMed
  21. White CE, et al. 2015. J Immunol. 194:697. PubMed
  22. Lu X, et al. 2015. J Immunol. 194:2011. PubMed
  23. Radtke?AJ,?et al.?2020.?Proc Natl Acad Sci U S A.?117:33455-65. (SB)?PubMed
  24. Radtke?AJ,?et al.?2022.?Nat Protoc.?17:378-401. (SB)?PubMed
Product Citations
  1. Heindl S, et al. 2021. J Exp Med. 218:. PubMed
  2. Xiong W, et al. 2022. Nat Commun. 13:1700. PubMed
  3. Sasaki I, et al. 2012. Blood. 120:4733. PubMed
  4. Koyama M, et al. 2015. J Exp Med. 212: 1303 - 1321. PubMed
  5. Sun L, et al. 2021. Cancer Cell. :. PubMed
  6. Sierro F, et al. 2017. Immunity. 47:374. PubMed
  7. Tomida S, et al. 2019. Sci Rep. 9:10751. PubMed
  8. Yu X, et al. 2020. Nat Commun. 11:1110. PubMed
  9. Huang J, et al. 2022. J Transl Med. 20:496. PubMed
  10. Kitagawa S, et al. 2022. NPJ Vaccines. 7:115. PubMed
  11. Ortiz G, et al. 2020. Front Immunol. 11:1713. PubMed
  12. Herz J, et al. 2015. J Exp Med. 212: 1153 - 1169. PubMed
  13. Lino AC et al. 2018. Immunity. 49(1):120-133 . PubMed
  14. Farsakoglu Y et al. 2019. Cell reports. 26(9):2307-2315 . PubMed
  15. Aldon Y, et al. 2020. J Immunol. 204:903. PubMed
  16. Deslyper G, et al. 2021. Parasitology. 148:539. PubMed
  17. Devalaraja S, et al. 2020. Cell. 1098:180. PubMed
  18. Sari G, et al. 2020. Biochem Biophys Res Commun. 510:524. PubMed
  19. Clement M, et al. 2016. PLoS Pathog. 12:e1006050. PubMed
  20. Yoshioka D, et al. 2016. Antimicrob Agents Chemother. 60: 6146 - 6154. PubMed
  21. Shon W, et al. 2015. Sci Rep. 5:17305. PubMed
  22. Han Y, et al. 2020. Nat Commun. 11:1776. PubMed
  23. Periasamy S, et al. 2017. Nat Commun. 8:15564. PubMed
  24. Choi H et al. 2019. Cell Rep. 27(3):806-819 . PubMed
  25. Casali P, et al. 2021. Front Immunol. 12:761450. PubMed
  26. Xu F, et al. 2022. Cell Death Discov. 8:142. PubMed
  27. Hayatsu N et al. 2017. Immunity. 47(2):268-283 . PubMed
  28. Li Y, et al. 2022. Clin Transl Immunology. 11:e1362. PubMed
  29. Haugh KA, et al. 2021. eLife. 0.416666666666667. PubMed
  30. Sharma S, et al. 2015. J Immunol. 194:5529. PubMed
  31. Yoshimi A, et al. 2019. Nature. 574:273. PubMed
  32. Devalaraja S, et al. 2020. STAR Protoc. 1:100188. PubMed
  33. K?lle J, et al. 2022. iScience. 25:104440. PubMed
  34. Salei N, et al. 2020. J Am Soc Nephrol. 31:257. PubMed
  35. Zhao F, et al. 2022. Front Immunol. 13:873720. PubMed
  36. Metzger D, et al. 2015. J Infect Dis. 212: 445-452. PubMed
  37. Dos Santos Dias L, et al. 2021. PLoS Pathog. e1009324:17. PubMed
  38. Uchil PD et al. 2018. Cell host & microbe. 25(1):87-100 . PubMed
  39. Kotaki R, et al. 2020. Sci Rep. 10:13554. PubMed
  40. Trompette A, et al. 2022. Mucosal Immunol. :. PubMed
  41. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  42. Hurrell BP, et al. 2019. Cell Rep. 29:4509. PubMed
  43. Liu D et al. 2019. Immunity. 51(1):64-76 . PubMed
  44. Friedman DJ, et al. 2021. Cancer Immunol Res. 9:952. PubMed
  45. Zhang K, et al. 2014. PLoS Pathog. 10:1004385. PubMed
  46. Furuya Y, et al. 2015. PLoS Pathog. 11: 1005180. PubMed
  47. Wessel AW, et al. 2020. Nat Commun. 4.123611111. PubMed
  48. Noah AC, et al. 2020. J Appl Physiol (1985). 473:128. PubMed
  49. Proto JD et al. 2018. Immunity. 49(4):666-677 . PubMed
  50. Takano T, et al. 2020. Front Immunol. 11:1555. PubMed
  51. Panea C, et al. 2021. Commun Biol. 4:913. PubMed
  52. Mulas F, et al. 2020. Cell Mol Immunol. . PubMed
  53. Viana C, et al. 2015. PLoS One. 10: 0130809. PubMed
  54. Davis M, et al. 2015. J Immunol. 194:2219. PubMed
  55. Suresh MV, et al. 2019. JCI Insight. 4:e133103. PubMed
  56. Zerif E, et al. 2020. Int J Mol Sci. 21:. PubMed
  57. Ariyoshi Y, et al. 2016. Gene Ther. 10.1038/gt.2016.7. PubMed
  58. Zeng W, et al. 2021. STAR Protocols. 2(1):100361. PubMed
  59. Branchett WJ, et al. 2020. Wellcome Open Research. 0.278472222. PubMed
  60. Lin J, et al. 2021. Nat Commun. 12:5321. PubMed
  61. Galle-Treger L, et al. 2020. J Allergy Clin Immunol. 145:502. PubMed
  62. Shafiei-Jahani P, et al. 2021. Nat Commun. 12:2526. PubMed
  63. Walsh SM, et al. 2021. eLife. 10:00. PubMed
  64. Galle-Treger L, et al. 2016. Nat Commun. 7:13202. PubMed
  65. Kim P, et al. 2015. Infect Immun . 83: 2992 - 3002. PubMed
  66. Ballet R, et al. 2014. PLoS Pathog. 10:1004550. PubMed
  67. Nair S, et al. 2021. JCI Insight. 6:. PubMed
  68. Yang X, et al. 2022. Front Immunol. 13:856230. PubMed
  69. Alam Z, et al. 2020. Cell Rep. 107825:31. PubMed
  70. Echevarría-Vargas IM, et al. 2018. EMBO Mol Med. 10:e8446. PubMed
  71. Galle-Treger L, et al. 2019. Nat Commun. 10:713. PubMed
  72. Zhang W, et al. 2020. Nat Commun. 11:1187. PubMed
  73. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  74. Shibuya M, et al. 2021. iScience. 24:103131. PubMed
  75. Mansouri S, et al. 2020. Mucosal Immunol. 0.954861111. PubMed
  76. Sasaki Y, et al. 2015. PLoS One. 10: 0131176. PubMed
  77. Spangenberg E, et al. 2019. Nat Commun. 10:3758. PubMed
  78. Lee H, et al. 2017. J Immunol. 199:1453. PubMed
  79. Calderon B, et al. 2015. J Exp Med. 212: 1497-1512. PubMed
  80. Guendel F, et al. 2020. Immunity. 53(5):1015-1032.e8. PubMed
  81. Chakraborty M, et al. 2021. Cell Reports. 34(2):108609. PubMed
  82. Draijer C, et al. 2018. Sci Rep. 8:5105. PubMed
  83. Wang T et al. 2018. Immunity. 49(3):504-514 . PubMed
  84. Darling R, et al. 2020. Int J Nanomedicine. 5.19375. PubMed
  85. Tulyeu J, et al. 2021. Curr Protoc. 1:e283. PubMed
  86. Zheng Y, et al. 2022. J Immunol. 208:501. PubMed
  87. Xiao Y, et al. 2021. Cell. 184:6037. PubMed
  88. Issah Y, et al. 2021. Elife. 10:. PubMed
  89. Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
  90. Zhao N, et al. 2018. J Clin Invest. 26:84. PubMed
  91. Konda P, et al. 2022. Am J Cancer Res. 12:210. PubMed
  92. Yin X, et al. 2020. Cell Rep. 33:108278. PubMed
  93. Huang WC, et al. 2020. Adv Mater. 32:e2005637. PubMed
  94. Ubags ND, et al. 2021. J Allergy Clin Immunol. 1049:147. PubMed
  95. Zhang L, et al. 2020. Cell. 442:181. PubMed
  96. Sheng J, et al. 2021. eLife. 10:00. PubMed
  97. Khan S, et al. 2016. J Exp Med. 213(13):2913-2929. PubMed
  98. Ramanan D, et al. 2020. Cell. 181(6):1276-1290. PubMed
  99. Mogilenko DA et al. 2019. Cell. 177(5):1201-1216 . PubMed
  100. White JP et al. 2018. Cell. 175(5):1198-1212 . PubMed
  101. Lau A, et al. 2022. Sci Adv. 8:eabm0142. PubMed
  102. Mansouri S, et al. 2021. J Immunol. 206:2233. PubMed
  103. Strait AA, et al. 2021. Commun Biol. 4:1005. PubMed
  104. Lerbs T, et al. 2020. JCI Insight. 5:00. PubMed
  105. Zhu Y et al. 2017. The Journal of Neuroscience. 37(9):2362-2376 . PubMed
  106. Zhang SJ, et al. 2021. Adv Sci (Weinh). 8:2003410. PubMed
  107. Hohsfield LA, et al. 2021. Elife. 10:. PubMed
  108. Lucas ED, et al. 2020. Cell Reports. 33(2):108258. PubMed
  109. Choi J, et al. 2013. PLoS Negl Trop Dis. 7:e1981. PubMed
  110. Qi S, et al. 2020. Theranostics. 10:1814. PubMed
  111. Kim I et al. 2015. Brain and behavior. 5(12):e00403 . PubMed
  112. Kubli SP, et al. 2019. Nat Commun. 10:2678. PubMed
  113. Aurélien Trompette et al. 2018. Immunity. 48(5):992-1005 . PubMed
RRID
AB_830646 (BioLegend Cat. No. 117323) AB_830649 (BioLegend Cat. No. 117324)

Antigen Details

Structure
Integrin α-chain, associates with integrin β2 (CD18), 150 kD
Distribution

Dendritic cells, NK cells, intestinal intraepithelial lymphocytes (IEL), some activated T cells

Function
Cellular adhesion
Ligand/Receptor
iC3b, fibrinogen
Cell Type
Dendritic cells, Epithelial cells, NK cells, T cells, Tregs
Biology Area
Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Barclay A, et al. 1997. The Leukocyte Antigen Facts Book Academic Press.
2. Springer TA. 1994. Cell 76:301.
3. Lopez-Rodriguez C, et al. 1996. J. Immunol. 156:3780.

Gene ID
16411 View all products for this Gene ID
UniProt
View information about CD11c on UniProt.org

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