Purified anti-FIG4/SAC3 Antibody
- 产品名称：
- Purified anti-FIG4/SAC3 Antibody
- 产品类别：
- 抗体
- 产品编号：
- 861801
- 产品应用：
- 861801
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Fusion protein amino corresponding to amino acids 688-907 (C-terminus) of mouse FIG4.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2801233 (BioLegend Cat. No. 861801) AB_2801234 (BioLegend Cat. No. 861802)
- Structure
- Human FIG4 is a 907 amino acid protein with a molecular mass of 103 kD.
- Distribution
-
Tissue distribution: ubiquitously expressed.
Cellular source: plasma membrane, endoplasmic reticulim, endosome, golgi apparatus, intracellular membrane, and vacuoles.
- Function
- FIG4 is involved in the regulation of phosphoinositides levels and intracellular vesicle trafficking.
- Interaction
- Interacts with FAB1 and VAC14
- Cell Type
- Neurons
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Synaptic Biology
- Molecular Family
- Protein Kinases/Phosphatase, Synaptic Vesicle Trafficking/Endocytosis
- Antigen References
-
- Chow C. et al. 2007. Nature. 448(7149):68-72.
- Chow C. et al. 2009. Am J Hum Genet. 84(1):85-8.
- Lenk G.M. et al. 2011. PLoS Genet. 7(6):e1002104.
- Gene ID
- 9896 View all products for this Gene ID 103199 View all products for this Gene ID 309855 View all products for this Gene ID
- UniProt
- View information about FIG4/SAC3 on UniProt.org
