Purified anti-NALCN Antibody
- 产品名称：
- Purified anti-NALCN Antibody
- 产品类别：
- 抗体
- 产品编号：
- 857201
- 产品应用：
- 857201
- Verified Reactivity
- Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Fusion protein corresponding to amino acids 1659-1738 (cytoplasmic C-terminus) of rat NALCN
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 - 5.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2783469 (BioLegend Cat. No. 857201) AB_2783470 (BioLegend Cat. No. 857202)
- Structure
- Rodent NALCN is a 1,738 amino acid protein with a molecular mass of 200 kD.
- Distribution
-
Tissue distribution: Brain, spinal cord, heart, pituitary and adrenal glands, and pancreatic islet cells.
Cellular distribution: Plasma membrane.
- Function
- NALCN participates in facilitating intracellular transport of sodium, modulation of neuronal excitability, and maintenance of respiratory rhythm.
- Interaction
- Substance P (SP), Substance P receptor (SPR), Src family of tyrosine kinases (SFK), mUNC80, M3 muscarinic receptor (M3R)
- Biology Area
- Cell Biology, Neuroscience, Synaptic Biology
- Molecular Family
- Adhesion Molecules
- Antigen References
-
- Lu B, et al. 2007. Cell.?129(2):371-83.
- Lu B, et al. 2010. Neuron. 68(3):488-99.?
- Swayne LA, et al. 2009. EMBO Rep. 10: 873–880.
- Gene ID
- 338370 View all products for this Gene ID 266760 View all products for this Gene ID
- UniProt
- View information about NALCN on UniProt.org
