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首页 > 抗体蛋白 > 抗体
HRP anti-HCN4 Antibody
产品名称：
HRP anti-HCN4 Antibody
产品类别：
抗体
产品编号：
857004
产品应用：
857004
[价格]
规格 价格 库存
100µg ￥ 2400 1

产品详情

Product Details

Verified Reactivity
Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Fusion protein corresponding to amino acids 1021-1110 (cytoplasmic C-terminus) of human HCN4
Formulation
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Preparation
The antibody was purified by affinity chromatography and conjugated with HRP under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
Upon receipt, the antibody solution should be stored undiluted at -20°C, and protected from prolonged exposure to light.
Application

WB - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 1.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2810726 (BioLegend Cat. No. 857004)

Antigen Details

Structure
HCN4 is a 1,186 amino acid protein with a molecular mass of 127 kD.
Distribution

Tissue distribution: Brain, heart, adrenal gland, and testis.
Cellular distribution: Membrane.

Function
HCN4 generates inward current If in the heart and Ih in the brain, and modulates intrinsic neuronal excitability and synaptic integrity.
Interaction
HCN4 interacts with other HCN subunits (HCN1-3) to form a functional channel.
Cell Type
Neurons
Biology Area
Cell Biology, Neuroscience, Synaptic Biology
Molecular Family
Presynaptic proteins
Antigen References
  1. Kelmendi, B. et al. 2011. Neurosci Lett. 496(3): 195–199.
  2. Stieber, J. et al. 2003. Proc Natl Acad Sci U S A. 100(25):15235-40.
  3. Xu, X. et al. 2010. J Biol Chem. 285(47):37082-91.
Gene ID
330953 View all products for this Gene ID 59266 View all products for this Gene ID
UniProt
View information about HCN4 on UniProt.org

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