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FITC anti-rat CD49d Antibody
产品名称:
FITC anti-rat CD49d Antibody
产品类别:
抗体
产品编号:
200103
产品应用:
200103
[价格]
规格 价格 库存
50µg ¥ 1212 1

产品详情

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
RBL-2H3 rat basophilic leukemia cell line
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications include: immunoprecipitation1, in vitro activation, in vitro inhibition1 of binding of VCAM-1 and mast cells to fibronectin , and in vivo inhibition of VLA-4 functions1. The LEAF? purified antibody (Endotoxin <0.1 EU/?g, Azide-Free, 0.2 ?m filtered) is recommended for functional assays (Cat. No. 200106).

Application References

(PubMed link indicates BioLegend citation)
  1. Yasuda M, et al. 1995. Int. Immunol. 7:251. (IP, Block)
Product Citations
  1. Greis C, et al. 2017. Crit Care. 10.1186/s13054-017-1654-9. PubMed
  2. Jiang M, et al. 2020. Exp Ther Med. 1.989583333. PubMed
  3. Felce JH, et al. 2018. Sci Signal. 11:eaat0756. PubMed
RRID
AB_2265193 (BioLegend Cat. No. 200103)

Antigen Details

Structure
Integrin α chain, 150 kD
Distribution

α41- peripheral T cells and B cell lymphocytes, thymocytes, and monocytes; α47- peripheral lymphocytes

Function
Adhesion
Ligand/Receptor
CD106 (VCAM-1), MAdCAM-1, fibronectin
Cell Type
B cells, Lymphocytes, Monocytes, T cells, Thymocytes
Biology Area
Immunology
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Yasuda, M., et al. 1995. Int. Immunol. 7:251.
2. Springer, T.A. 1994. Cell 76:301.
3. Issekutz, T. B., et al. 1991. J. Immunol. 147:4178.
4. Issekutz, T. B., et al. 1991. J. Immunol. 147:109.
5. Yang, H., et al. 1995. Transplantation 60:71.
6. Palecanda, A., et al. 1997. J. Immunol. 158:2904.

Gene ID
311144 View all products for this Gene ID
UniProt
View information about CD49d on UniProt.org

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