首页 > 抗体蛋白 > 抗体
FITC anti-human MRP-14 (S100A9) Antibody
产品名称:
FITC anti-human MRP-14 (S100A9) Antibody
产品类别:
抗体
产品编号:
350703
产品应用:
350703
[价格]
规格 价格 库存
25tests ¥ 1344 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human MRP-14
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions.
Concentration
Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

ICFC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.

Excitation Laser
Blue Laser (488 nm)
Application Notes

This clone has been published as 1H9.

Additional reported applications (for the relevant formats) include: Western blotting1 and immunohistochemical staining? with paraffin-embedded tissue sections1,2.

Application References

(PubMed link indicates BioLegend citation)
  1. Robinson MJ, et al. 2002. J. Biol. Chem. 277:3658. (WB, IHC)
  2. Croce K, et al. 2009. Circulation 120:427. (IHC)
  3. Andricovich J, et al. 2016. J. Clin. Invest. 126:905. (ICFC) Pubmed
Product Citations
  1. Yoshida M, et al. 2022. Nature. 602:321. PubMed
RRID
AB_10662414 (BioLegend Cat. No. 350703) AB_10662250 (BioLegend Cat. No. 350704)

Antigen Details

Structure
Belongs to S100 family of proteins containing 2-EF-hand calcium -binding motifs, forms non-covalently associated complexes with another S100 family member MRP-8
Distribution

MDSCs, neutrophils, monocyte, and ileal tissue eosinophils

Function
Calcium-dependent activation, immunomodulating and antiproliferative, endogenous activator of Toll-like receptor 4
Interaction
Calcium
Cell Type
Neutrophils, Monocytes, Eosinophils
Biology Area
Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Signal Transduction
Molecular Family
Adhesion Molecules
Antigen References

1. Loser K, et al. 2010. Nat. Med. 16:713.
2. Cheng P, et al. 2008. J. Exp. Med. 205:2235.
3. Leukert N, et al.2006. J. Mol. Biol. 359:961.
4. Lagasse E, et al. 1988. Mol. Cell. Biol. 8:2402.
5. Zhao F, et al. 2012. Immunology. 136:176.?

Gene ID
6280 View all products for this Gene ID
UniProt
View information about MRP-14 on UniProt.org

联系我们

TEL:021-34661275  点击拨打热线