APC anti-human MRP-14 (S100A9) Antibody
- 产品名称：
- APC anti-human MRP-14 (S100A9) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 350707
- 产品应用：
- 350707
[价格]
| 规格 |
价格 |
库存 |
| 25tests |
￥ 1704 |
1 |
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human MRP-14
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Application Notes
This clone has been published as 1H9.
Additional reported applications (for the relevant formats) include: Western blotting1 and immunohistochemical staining? with paraffin-embedded tissue sections1,2.
- Application References
(PubMed link indicates BioLegend citation) -
- Robinson MJ, et al. 2002. J. Biol. Chem. 277:3658. (WB, IHC)
- Croce K, et al. 2009. Circulation 120:427. (IHC)
- Andricovich J, et al. 2016. J. Clin. Invest. 126:905. (ICFC) Pubmed
- Product Citations
-
- Kwak T, et al. 2020. Cell Reports. 33(13):108571. PubMed
- RRID
- AB_2564009 (BioLegend Cat. No. 350707) AB_2564010 (BioLegend Cat. No. 350708)
- Structure
- Belongs to S100 family of proteins containing 2-EF-hand calcium -binding motifs, forms non-covalently associated complexes with another S100 family member MRP-8
- Distribution
-
MDSCs, neutrophils, monocyte, and ileal tissue eosinophils
- Function
- Calcium-dependent activation, immunomodulating and antiproliferative, endogenous activator of Toll-like receptor 4
- Interaction
- Calcium
- Cell Type
- Neutrophils, Monocytes, Eosinophils
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- Adhesion Molecules
- Antigen References
-
1. Loser K, et al. 2010. Nat. Med. 16:713.
2. Cheng P, et al. 2008. J. Exp. Med. 205:2235.
3. Leukert N, et al.2006. J. Mol. Biol. 359:961.
4. Lagasse E, et al. 1988. Mol. Cell. Biol. 8:2402.
5. Zhao F, et al. 2012. Immunology. 136:176.?
- Gene ID
- 6280 View all products for this Gene ID
- UniProt
- View information about MRP-14 on UniProt.org
