Purified anti-rat CD106 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
50µg	￥ 924	1

Product Details

Verified Reactivity

Rat

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Rat VCAM-1 transfected L5178Y cells

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

FC - Quality tested
IHC-F - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections^1,2,3.

Application References (PubMed link indicates BioLegend citation)

Bevilacqua, M.P. 1993. Annu. Rev. Immunol. 11:767. (IHC)
Wingerd, K.L., et al. 2002. J. Neuroscience 22:10772. (IHC)
Ogawa, T., et al. 2004. Am J. Physiol. Gastrointest. Liver Physiol. 286:G702. (IHC)

Product Citations

Amante F, et al. 2010. J Immunol. 185:3632. PubMed
Brooks M, et al. 2017. PLoS One. doi: 10.1371/journal.pone.0169976. PubMed

RRID

AB_2304304 (BioLegend Cat. No. 200401) AB_2214211 (BioLegend Cat. No. 200402)

Antigen Details

Structure: Ig superfamily, 110 kD
Distribution: Bone marrow stromal cells, myeloid cells, splenic dendritic cells, induced on endothelial cells
Function: Adhesion, leukocyte extravasation at sites of inflammation
Ligand/Receptor: VLA-4 (α₄/β₁ integrin) and LPAM-1 (α₄/β₇ integrin)
Cell Type: Dendritic cells, Endothelial cells
Biology Area: Cell Biology, Immunology, Neuroinflammation, Neuroscience
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Barclay, A.N., et al. 1997. The Leukocyte Antigen FactsBook. Academic Press.
2. Kinashi, T., et al. 1995. J. Leuk. Biol. 57:168.
3. Bevilacquea, M.P., 1993. Ann. Rev. Immunol. 11:767.
4. Koni, P.A., et al. 2001. J. Exp. Med. 193:741.
Gene ID: 22329 View all products for this Gene ID
UniProt: View information about CD106 on UniProt.org

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