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Purified anti-mouse/human Siglec-15 Antibody
产品名称：
Purified anti-mouse/human Siglec-15 Antibody
产品类别：
抗体
产品编号：
164602
产品应用：
164602
[价格]
规格 价格 库存
100µg ￥ 3312 1

产品详情

Product Details

Verified Reactivity
Mouse, Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Mouse Siglec-15-huIgG Fc fusion protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
ICC, ICFC, Direct ELISA, ELISA Capture - Reported in the literature, not verified in house
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application References

(PubMed link indicates BioLegend citation)
  1. Korn M, et al. 2020. J Immunol. 205:2595-2605.
RRID
AB_2922502 (BioLegend Cat. No. 164602)

Antigen Details

Structure
Type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail
Distribution

Myeloid lineage, osteoclasts, and upregulated by certain types of human cancers

Function
Regulates osteoclast development and bone resorption
Interaction
DAP12
Ligand/Receptor
Neu5Ac alpha2-6GalNAc alpha
Cell Type
Macrophages, Osteoclasts
Biology Area
Immunology
Molecular Family
Siglec Molecules
Antigen References
  1. Wang J, et al. 2019. Nat Med. 25:656-666.
  2. Angata T. 2020. J Biomed Sci. 27:10.
  3. Takamiya R, et al. 2013. Glycobiology. 23:178-87.
Gene ID
620235 View all products for this Gene ID 284266 View all products for this Gene ID
UniProt
View information about Siglec-15 on UniProt.org

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