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Purified anti-mouse CD105 Antibody
产品名称:
Purified anti-mouse CD105 Antibody
产品类别:
抗体
产品编号:
120401
产品应用:
120401
[价格]
规格 价格 库存
50µg ¥ 852 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Inflamed mouse skin
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested
IHC-F - Verified
WB, IP - Reported in the literature, not verified in house

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. For immunohistochemical staining on frozen tissue sections, the suggested use of this reagent is 5.0-10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Additional reported applications include: immunoprecipitation, Western blotting, and immunofluorescence histochemistry or immunohistochemistry of acetone-fixed frozen sections2-4.

Application References

(PubMed link indicates BioLegend citation)
  1. Ge AZ and Butcher EC. 1994. Gene 138:201.
  2. Baluk P, et al. 2003. Am. J. Pathol. 163:1801. (IHC)
  3. Takahashi T, et al. 2003. Mol. Cell Biol. 23:1817. (IHC)
  4. Savinov AY, et al. 2003. J. Exp. Med. 197:643. (IHC)
Product Citations
  1. Cao Y et al. 2018. Molecular metabolism. 14:71-81 . PubMed
  2. Scheller I, et al. 2021. Haematologica. . PubMed
  3. Sereni L, et al. 2018. J Allergy Clin Immunol. 142:1272. PubMed
  4. Zhang X, et al. 2022. Theranostics. 12:1621. PubMed
  5. Galaris G, et al. 2021. Int J Mol Sci. 22:. PubMed
  6. Stritt S, et al. 2016. Nat Commun. 7:11097. PubMed
  7. Lehmann ML, et al. 2020. Brain Behav Immun. 88:735. PubMed
  8. Zhu YP et al. 2018. Cell reports. 24(9):2329-2341 . PubMed
  9. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
RRID
AB_961066 (BioLegend Cat. No. 120401) AB_961070 (BioLegend Cat. No. 120402)

Antigen Details

Structure
Type I integral membrane protein, homodimer, TGF-β type III receptor family member
Distribution

Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotrophoblast

Function
Suppresses TGF-β signaling, angiogenesis
Ligand/Receptor
TGF-β1, TGF-β3
Cell Type
Endothelial cells, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area
Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Gougos A and M. Letarte 1988. J. Immunol. 141:1925.
2. Cheifetz S, et al. 1992. J. Bio. Chem. 267:19027.
3. Barbara NP, et al. 1999. J. Bio. Chem. 274:584.
4. Lastres P, et al. 1992. Eur. J. Immunol. 22:393.
5. Duff S, et al. 2003. FASEB J. 17:984.
6. Warrington K, et al. 2005. Anticancer Res. 25:185.

Gene ID
13805 View all products for this Gene ID
UniProt
View information about CD105 on UniProt.org

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