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PE/Cyanine7 anti-mouse CD105 Antibody
产品名称:
PE/Cyanine7 anti-mouse CD105 Antibody
产品类别:
抗体
产品编号:
120409
产品应用:
120409
[价格]
规格 价格 库存
25µg ¥ 1764 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Inflamed mouse skin
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE/Cyanine7 under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications include: immunoprecipitation, Western blotting, and immunofluorescence histochemistry or immunohistochemistry of acetone-fixed frozen sections2-4.

Additional Product Notes
BioLegend is in the process of converting the name PE/Cy7 to PE/Cyanine7. The dye molecule remains the same, so you should expect the same quality and performance from our PE/Cyanine7 products. Please contact Technical Service if you have any questions.
Application References

(PubMed link indicates BioLegend citation)
  1. Ge AZ and Butcher EC. 1994. Gene 138:201.
  2. Baluk P, et al. 2003. Am. J. Pathol. 163:1801. (IHC)
  3. Takahashi T, et al. 2003. Mol. Cell Biol. 23:1817. (IHC)
  4. Savinov AY, et al. 2003. J. Exp. Med. 197:643. (IHC)
Product Citations
  1. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  2. Chaugule S, et al. 2021. Int J Mol Sci. 22:. PubMed
  3. Davis FM, et al. 2020. J Immunol. 2503:204. PubMed
  4. Feng H, et al. 2020. J Clin Invest. 130:6354. PubMed
  5. Weng L, et al. 2016. Sci Rep. 6:38632. PubMed
  6. Derby B, et al. 2014. Aesthet Surg J. 34:142. PubMed
  7. Baryawno N et al. 2019. Cell. 177(7):1915-1932 . PubMed
  8. Hu X, et al. 2016. Nat Commun. 7:13095. PubMed
  9. Szade K, et al. 2013. PLoS One. 8:63329. PubMed
  10. Bowers E, et al. 2018. Nat Med. 24:95. PubMed
  11. AR P, et al. 2016. Circ Res. 118: 400-409. PubMed
  12. Davis FM, et al. 2019. Arterioscler Thromb Vasc Biol. 39:2353. PubMed
  13. Higashi AY, et al. 2019. J Am Soc Nephrol. 30:80. PubMed
  14. Nakamura‐Ishizu A et al. 2018. Cell reports. 25(7):1772-1785 . PubMed
  15. Jumabay M, et al. 2022. Sci Rep. 12:5614. PubMed
  16. Lin C, et al. 2022. Nat Commun. 13:6869. PubMed
  17. Rebekka K Schneider et al. 2017. Cell stem cell. 20(6):785-800 . PubMed
  18. Farsaci B, et al. 2014. Cancer Immunol Res. 2:1090. PubMed
  19. Yang S, et al. 2022. J Exp Med. 219:. PubMed
  20. Jing Y, et al. 2020. Cancer Gene Ther. 27:910. PubMed
  21. Philip E Boulais et al. 2018. Immunity. 49(4):627-639 . PubMed
  22. Matsumura T, et al. 2022. Nat Commun. 13:7064. PubMed
  23. Labedz-Maslowska A, et al. 2015. PLoS One. 10: 0133746. PubMed
  24. Kim JM, et al. 2020. Nat Commun. 11:2289. PubMed
  25. S?wen P et al. 2018. eLife. 7 pii: e41258. PubMed
  26. Agarwal P, et al. 2021. Cell Reports. 36(2):109386. PubMed
  27. Severe N et al. 2019. Cell Stem Cell. 25(4):570-583 . PubMed
  28. Wang L, et al. 2020. Nat Commun. 0.654166667. PubMed
  29. Han Y, et al. 2019. J Clin Invest. 130:26. PubMed
RRID
AB_1027702 (BioLegend Cat. No. 120409) AB_1027700 (BioLegend Cat. No. 120410)

Antigen Details

Structure
Type I integral membrane protein, homodimer, TGF-β type III receptor family member
Distribution

Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotrophoblast

Function
Suppresses TGF-β signaling, angiogenesis
Ligand/Receptor
TGF-β1, TGF-β3
Cell Type
Endothelial cells, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area
Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Gougos A and M. Letarte 1988. J. Immunol. 141:1925.
2. Cheifetz S, et al. 1992. J. Bio. Chem. 267:19027.
3. Barbara NP, et al. 1999. J. Bio. Chem. 274:584.
4. Lastres P, et al. 1992. Eur. J. Immunol. 22:393.
5. Duff S, et al. 2003. FASEB J. 17:984.
6. Warrington K, et al. 2005. Anticancer Res. 25:185.

Gene ID
13805 View all products for this Gene ID
UniProt
View information about CD105 on UniProt.org

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