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PE anti-mouse CD105 Antibody
产品名称:
PE anti-mouse CD105 Antibody
产品类别:
抗体
产品编号:
120407
产品应用:
120407
[价格]
规格 价格 库存
25µg ¥ 1104 1

产品详情

Product Details

Verified Reactivity
Mouse
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Inflamed mouse skin
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 ?g per 106 cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application Notes

Additional reported applications include: immunoprecipitation, Western blotting, and immunofluorescence histochemistry or immunohistochemistry of acetone-fixed frozen sections2-4.

Application References

(PubMed link indicates BioLegend citation)
  1. Ge AZ and Butcher EC. 1994. Gene 138:201.
  2. Baluk P, et al. 2003. Am. J. Pathol. 163:1801. (IHC)
  3. Takahashi T, et al. 2003. Mol. Cell Biol. 23:1817. (IHC)
  4. Savinov AY, et al. 2003. J. Exp. Med. 197:643. (IHC)
Product Citations
  1. Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
  2. Lawson H, et al. 2021. Stem Cell Reports. 16:2784. PubMed
  3. Fan C, et al. 2020. Stem Cell Res Ther. 0.765277778. PubMed
  4. Silva C, et al. 2019. Cell Physiol Biochem. 52:503. PubMed
  5. Huang Z, et al. 2020. Mol Med Rep. 1.979166667. PubMed
  6. Mittal S, et al. 2016. Stem Cell Reports. 7:583-590. PubMed
  7. Zhang W, et al. 2021. Cell Prolif. 54:e13058. PubMed
  8. Khoramian Tusi B, et al. 2018. Exp Hematol. 60:21. PubMed
  9. Hou M, et al. 2020. Stem Cell Res Ther. 11:55. PubMed
  10. Uribesalgo I, et al. 2019. EMBO Mol Med. 11:e9266. PubMed
  11. Zhao X, et al. 2022. Biomed Opt Express. 13:791. PubMed
  12. Babazadeh S, et al. 2021. Cell Mol Biol Lett. 26:30. PubMed
  13. La Salvia S, et al. 2020. Am J Physiol Renal Physiol. 319:F868. PubMed
  14. Nakagawa MM, et al. 2018. Cell Rep. 25:2094. PubMed
  15. Franklin R, et al. 2022. Nat Commun. 13:2350. PubMed
  16. Vogiatzi A, et al. 2021. Mol Cell Biol. 41:e0014921. PubMed
RRID
AB_1027701 (BioLegend Cat. No. 120407) AB_1027699 (BioLegend Cat. No. 120408)

Antigen Details

Structure
Type I integral membrane protein, homodimer, TGF-β type III receptor family member
Distribution

Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotrophoblast

Function
Suppresses TGF-β signaling, angiogenesis
Ligand/Receptor
TGF-β1, TGF-β3
Cell Type
Endothelial cells, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area
Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family
Adhesion Molecules, CD Molecules
Antigen References

1. Gougos A and M. Letarte 1988. J. Immunol. 141:1925.
2. Cheifetz S, et al. 1992. J. Bio. Chem. 267:19027.
3. Barbara NP, et al. 1999. J. Bio. Chem. 274:584.
4. Lastres P, et al. 1992. Eur. J. Immunol. 22:393.
5. Duff S, et al. 2003. FASEB J. 17:984.
6. Warrington K, et al. 2005. Anticancer Res. 25:185.

Gene ID
13805 View all products for this Gene ID
UniProt
View information about CD105 on UniProt.org

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