Pacific Blue™ anti-mouse CD105 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1212	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Inflamed mouse skin

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography, and conjugated with Pacific Blue? under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per 10⁶ cells in 100 ?l volume or 100 ?l of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* Pacific Blue? has a maximum emission of 455 nm when it is excited at 405 nm. Prior to using Pacific Blue? conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses

Excitation Laser

Violet Laser (405 nm)

Application Notes

Additional reported applications include: immunoprecipitation, Western blotting, and immunofluorescence histochemistry or immunohistochemistry of acetone-fixed frozen sections^2-4.

Application References (PubMed link indicates BioLegend citation)

Ge AZ and Butcher EC. 1994. Gene 138:201.
Baluk P, et al. 2003. Am. J. Pathol. 163:1801. (IHC)
Takahashi T, et al. 2003. Mol. Cell Biol. 23:1817. (IHC)
Savinov AY, et al. 2003. J. Exp. Med. 197:643. (IHC)

Product Citations

Grigsby SM, et al. 2021. Cancers (Basel). 13:. PubMed
Lang J, et al. 2020. Nat Commun. 11:1338. PubMed
Oh D, et al. 2012. J Immunol. 188:2207. PubMed
Kleppe M et al. 2018. Cancer cell. 33(1):29-43 . PubMed
Marinescu CI, et al. 2021. Stem Cell Res Ther. 12:319. PubMed
van Gastel N, et al. 2020. Cell Metabolism. 32(3):391-403.e6. PubMed
Fischer KC, et al. 2021. Cell Death Dis. 12:28. PubMed
Tournaire G, et al. 2020. Bone. 115259:133. PubMed
Spevak CC, et al. 2020. Cell Stem Cell. 26(5):755-765. PubMed

RRID

AB_1877185 (BioLegend Cat. No. 120411) AB_2098890 (BioLegend Cat. No. 120412)

Antigen Details

Structure: Type I integral membrane protein, homodimer, TGF-β type III receptor family member
Distribution: Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotrophoblast
Function: Suppresses TGF-β signaling, angiogenesis
Ligand/Receptor: TGF-β1, TGF-β3
Cell Type: Endothelial cells, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Gougos A and M. Letarte 1988. J. Immunol. 141:1925.
2. Cheifetz S, et al. 1992. J. Bio. Chem. 267:19027.
3. Barbara NP, et al. 1999. J. Bio. Chem. 274:584.
4. Lastres P, et al. 1992. Eur. J. Immunol. 22:393.
5. Duff S, et al. 2003. FASEB J. 17:984.
6. Warrington K, et al. 2005. Anticancer Res. 25:185.
Gene ID: 13805 View all products for this Gene ID
UniProt: View information about CD105 on UniProt.org

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