APC anti-mouse CD105 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1080	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Inflamed mouse skin

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.

Concentration

0.2 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser

Red Laser (633 nm)

Application Notes

Additional reported applications include: immunoprecipitation, Western blotting, and immunofluorescence histochemistry or immunohistochemistry of acetone-fixed frozen sections^2-4.

Application References (PubMed link indicates BioLegend citation)

Ge AZ and Butcher EC. 1994. Gene 138:201.
Baluk P, et al. 2003. Am. J. Pathol. 163:1801. (IHC)
Takahashi T, et al. 2003. Mol. Cell Biol. 23:1817. (IHC)
Savinov AY, et al. 2003. J. Exp. Med. 197:643. (IHC)

Product Citations

Hutton C, et al. 2021. Cancer Cell. 39:1227. PubMed
Huang X, et al. 2021. Stem Cells Int. 2021:8138374. PubMed
Lai J, et al. 2021. Stem Cell Res. 55:102477. PubMed
Li Z, et al. 2022. Elife. 11:. PubMed
Liu H, et al. 2022. Nat Commun. 13:3684. PubMed
Hughes RM, et al. 2020. Cancer Research. 79(14):3636-3650.. PubMed
Galindo C, et al. 2014. J Am Heart Assoc. 3:773. PubMed
Zhu L, et al. 2021. Stem Cell Res Ther. 12:408. PubMed
Li Y, et al. 2020. Cell Stem Cell. 27(5):732-747.e7. PubMed
Formes H, et al. 2021. iScience. 24:103092. PubMed
Zhang H, et al. 2019. Mol Cell. 76:110. PubMed
Nanou A, et al. 2021. Cell Reports. 35(8):109168. PubMed
Chen R, et al. 2021. Cell Reports. 34(7):108751. PubMed
Yang P et al. 2019. Cell Syst. 8(5):427-445 . PubMed
Nenasheva T, et al. 2017. PLoS One. 12(6):e0178983. PubMed
Yamazaki M, et al. 2021. Biomedicines. 9:. PubMed
Jin Y, et al. 2020. PeerJ. 8:e10374. PubMed
Wang X, et al. 2018. Nat Commun. 9:551. PubMed
Fan X, et al. 2020. Acta Physiol (Oxf). 230:e13475. PubMed
Singhal P, et al. 2016. Proc Natl Acad Sci U S A. 113: 122 - 127. PubMed
Yang X, et al. 2021. Bioact Mater. 3150:6. PubMed
Woods B, et al. 2019. Clin Cancer Res. 25:5901. PubMed
Shao Y, et al. 2017. Endocrinology. 158:2722. PubMed
Lucotti S, et al. 2019. J Clin Invest. 130:1845. PubMed
Zhu Q, et al. 2021. J Am Heart Assoc. 10:e023491. PubMed
Thomson CA, et al. 2018. J Immunol. 201:215. PubMed

RRID

AB_2277915 (BioLegend Cat. No. 120413) AB_2277914 (BioLegend Cat. No. 120414)

Antigen Details

Structure: Type I integral membrane protein, homodimer, TGF-β type III receptor family member
Distribution: Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotrophoblast
Function: Suppresses TGF-β signaling, angiogenesis
Ligand/Receptor: TGF-β1, TGF-β3
Cell Type: Endothelial cells, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Gougos A and M. Letarte 1988. J. Immunol. 141:1925.
2. Cheifetz S, et al. 1992. J. Bio. Chem. 267:19027.
3. Barbara NP, et al. 1999. J. Bio. Chem. 274:584.
4. Lastres P, et al. 1992. Eur. J. Immunol. 22:393.
5. Duff S, et al. 2003. FASEB J. 17:984.
6. Warrington K, et al. 2005. Anticancer Res. 25:185.
Gene ID: 13805 View all products for this Gene ID
UniProt: View information about CD105 on UniProt.org

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