Alexa Fluor® 647 anti-mouse CD105 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1212	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Inflamed mouse skin

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 647 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

IHC-F - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunohistochemical staining on frozen tissue sections. For immunohistochemistry, a concentration range of 5.0 - 10.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

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Application Notes

Additional reported applications include: immunoprecipitation, Western blotting, and immunofluorescence histochemistry or immunohistochemistry of acetone-fixed frozen sections^2-4.

Application References (PubMed link indicates BioLegend citation)

Ge AZ and Butcher EC. 1994. Gene 138:201.
Baluk P, et al. 2003. Am. J. Pathol. 163:1801. (IHC)
Takahashi T, et al. 2003. Mol. Cell Biol. 23:1817. (IHC)
Savinov AY, et al. 2003. J. Exp. Med. 197:643. (IHC)

Product Citations

Comazzetto S et al. 2018. Cell stem cell. 24(3):477-486 . PubMed

RRID

AB_2728140 (BioLegend Cat. No. 120419) AB_2728141 (BioLegend Cat. No. 120420)

Antigen Details

Structure: Type I integral membrane protein, homodimer, TGF-β type III receptor family member
Distribution: Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotrophoblast
Function: Suppresses TGF-β signaling, angiogenesis
Ligand/Receptor: TGF-β1, TGF-β3
Cell Type: Endothelial cells, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Gougos A and M. Letarte 1988. J. Immunol. 141:1925.
2. Cheifetz S, et al. 1992. J. Bio. Chem. 267:19027.
3. Barbara NP, et al. 1999. J. Bio. Chem. 274:584.
4. Lastres P, et al. 1992. Eur. J. Immunol. 22:393.
5. Duff S, et al. 2003. FASEB J. 17:984.
6. Warrington K, et al. 2005. Anticancer Res. 25:185.
Gene ID: 13805 View all products for this Gene ID
UniProt: View information about CD105 on UniProt.org

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