Alexa Fluor® 488 anti-mouse CD105 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
25µg	￥ 1212	1

Product Details

Verified Reactivity

Mouse

Antibody Type

Monoclonal

Host Species

Rat

Immunogen

Inflamed mouse skin

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 ?g per million cells in 100 ?l volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.

Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.

View full statement regarding label licenses

Excitation Laser

Blue Laser (488 nm)

Application Notes

Additional reported applications include: immunoprecipitation, Western blotting, and immunofluorescence histochemistry or immunohistochemistry of acetone-fixed frozen sections^2-4.

Application References (PubMed link indicates BioLegend citation)

Ge AZ and Butcher EC. 1994. Gene 138:201.
Baluk P, et al. 2003. Am. J. Pathol. 163:1801. (IHC)
Takahashi T, et al. 2003. Mol. Cell Biol. 23:1817. (IHC)
Savinov AY, et al. 2003. J. Exp. Med. 197:643. (IHC)

Product Citations

Li Y, et al. 2015. J Immunol. 195: 2648-2656. PubMed
Berdnikovs S, et al. 2013. Am J Physiol Lung Cell Mol Physiol. 304:240. PubMed
Vijayaraj P, et al. 2019. Cell Rep. 29:3488. PubMed
Bai Y, et al. 2021. Front Cell Dev Biol. 9:730095. PubMed
Bahal R, et al. 2016. Nat Commun. 7:13304. PubMed
Quiroz HJ, et al. 2022. Front Cardiovasc Med. 8:826687. PubMed
Sanmarco LM, et al. 2021. Nature. 590:473. PubMed
Mesnieres M, et al. 2021. Cell Reports. 36(8):109618. PubMed
Clemente–Casares X, et al. 2017. Immunity. 47:974. PubMed
Yamada K, et al. 2016. Cancer Res . 76: 4283 - 4292. PubMed
Huang WC, et al. 2019. Int J Hyperthermia. 36:1255. PubMed

RRID

AB_961056 (BioLegend Cat. No. 120405) AB_961053 (BioLegend Cat. No. 120406)

Antigen Details

Structure: Type I integral membrane protein, homodimer, TGF-β type III receptor family member
Distribution: Endothelial cells, activated monocytes, macrophages, stromal cells, some cytotrophoblast
Function: Suppresses TGF-β signaling, angiogenesis
Ligand/Receptor: TGF-β1, TGF-β3
Cell Type: Endothelial cells, Macrophages, Mesenchymal Stem Cells, Monocytes
Biology Area: Angiogenesis, Cell Adhesion, Cell Biology, Immunology, Stem Cells
Molecular Family: Adhesion Molecules, CD Molecules
Antigen References: 1. Gougos A and M. Letarte 1988. J. Immunol. 141:1925.
2. Cheifetz S, et al. 1992. J. Bio. Chem. 267:19027.
3. Barbara NP, et al. 1999. J. Bio. Chem. 274:584.
4. Lastres P, et al. 1992. Eur. J. Immunol. 22:393.
5. Duff S, et al. 2003. FASEB J. 17:984.
6. Warrington K, et al. 2005. Anticancer Res. 25:185.
Gene ID: 13805 View all products for this Gene ID
UniProt: View information about CD105 on UniProt.org

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